Acne - Aknea
☆ Alemaniako Stiftung Warentest-en 2022ko emaitzetan, ModelDerm-ekin kontsumitzaileen gogobetetasuna apur bat txikiagoa izan zen ordaindutako telemedikuntzako kontsultekin baino.
Aknea enborraren eremuan. Enborraren goiko aldea eta bizkarra aknearen eremu arruntak dira.
References
Aknea, Estatu Batuetako larruazaleko gaixotasun ohikoena, larruazaleko hanturazko arazo iraunkor bat da. Tratamenduak aknea eragiten duten lau faktore nagusiei aurre egitea du helburu: gehiegizko sebumaren ekoizpena, azaleko zelulen pilaketa, Propionibacterium acnes kolonizazioa eta ondoriozko hantura. Erretinoide topikoek modu eraginkorrean kudeatzen dituzte hanturazko eta ez-hanturazko lesioak, komedonak prebenitu eta murriztuz, hanturari aurre egiten dioten bitartean. Benzoil peroxidoa, errezetarik gabe eskuragarri, bakterioen erresistentzia sustatu gabe agente bakterizida da. Topiko eta ahozko antibiotikoek bakarrik funtzionatzen duten bitartean, erretinoide topikoekin konbinatzeak eraginkortasuna hobetzen du. Antibiotiko terapiari benzoilo peroxidoa gehitzeak bakterioen erresistentzia izateko arriskua murrizten du. Ahozko isotretinoina, akne larri eta burugogorretarako onartua, iPLEDGE programaren bidez administratzen da.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Aknearen tratamendu topiko arruntak benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, and sulfone agents dira. Ahozko antibiotikoak aknearen tratamenduaren funtsezko atal bat izan dira aspalditik, batez ere kasu moderatu edo larrietarako. Onena funtzionatzen dute erretinoide topiko batekin eta BPrekin batera erabiltzen direnean. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, and cephalexin guztiek eraginkortasunaren froga erakutsi dute.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Erretinoide topikoak beti gomendatzen dira aknea tratatzeko. Antibiotiko sistemikoak edo topikoak erabiltzean, garrantzitsua da benzoil peroxidoarekin eta retinoideekin konbinatzea, baina 12 astez soilik. Isotretinoin beste tratamendu batzuei erantzun ez dieten akne kasu larrietarako gordeta dago. Laser terapia eta peeling kimikoak bezalako tratamendu fisikoen froga batzuk dauden arren, baita erleen pozoia araztua eta dieta batzuk bezalako planteamendu osagarriak ere, haien eraginkortasuna ez dago ziur.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Hainbat ikerketek elikagai ezberdinek akneari nola eragiten dioten aztertu dute. Karga gluzemiko baxua duten elikagaiak jaten dituzten aknea duten pertsonek akne-gune gutxiago izaten dituzte karga gluzemiko handiko elikagaiak jaten dituztenekin alderatuta. Esnekiak aknearekin lotuta ere aztertu dira. Badirudi esnean dauden proteina batzuek gantzak edo esne-eduki orokorrak baino akneari gehiago eragin diezaioketela. Beste ikerketa batzuk omega-3 gantz-azidoetan eta azido γ-linoleikoan zentratu dira. Aknea duten pertsonek arrain eta olio osasuntsu gehiago jateak onuragarria izan dezaketela iradokitzen du, gantz-azido horien ingesta handitzeko. Aknerako probiotikoei buruzko azken ikerketek emaitza itxaropentsuak erakusten dituzte, baina ikerketa gehiago behar dira aurkikuntza goiztiar hauek baieztatzeko.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Bi sexuetan, androgeno izeneko hormonak azpiko mekanismoaren parte direla dirudi, sebumaren ekoizpena areagotzea eraginez. Beste faktore arrunt bat azalean dagoen Cutibacterium acnes bakterioaren gehiegizko hazkuntza da.
Eragindako larruazalean zuzenean aplikatzen diren tratamenduak, hala nola, azido azelaikoa, benzoil peroxidoa eta azido salicilikoa erabiltzen dira. Antibiotikoak eta erretinoideak azalean aplikatzen diren eta aknearen tratamendurako ahoz hartzen diren formuletan daude eskuragarri. Hala ere, antibiotikoekiko erresistentzia garatu daiteke antibiotiko terapiaren ondorioz. Jaiotza-kontroleko pilulek emakumezkoen aknea prebenitzen lagun dezakete. Isotretinoina erabiliz aknearen tratamendu goiztiarra eta oldarkorra lagungarria izan daiteke epe luzerako konplikazioa gutxitzeko.
○ Tratamendua
Adapalene gela asko erabil daiteke, sebumaren jariapena kentzen duelako eta aknearen errepikapena kentzeko eragina duelako. Adapalene gelak azala narrita dezake hasieran gehiegi aplikatzen bada. Benzoil peroxidoa eta azido azelaikoa, berriz, hanturazko akne guneetan erabil daitezke, hantura laguntzen baitute. Oro har, epe luzeko tratamendua hilabete 1 edo gehiago behar da efektua ikusteko.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction