Intraepithelial carcinoma (Bowen disease)
☆ Alemaniako Stiftung Warentest-en 2022ko emaitzetan, ModelDerm-ekin kontsumitzaileen gogobetetasuna apur bat txikiagoa izan zen ordaindutako telemedikuntzako kontsultekin baino.
Kasu tipikoa ― Intraepithelial carcinoma (Bowen disease) iraupen luzeko eta azkurarik gabeko ekzema gisa diagnostikatu daiteke.
References
Bowen's disease (BD) azalaren kanpoko geruzan (epidermisa) hasten den azaleko minbizi mota bat da. Ohikoagoa da Kaukasiarrengan eta maiz eguzki-argiaren eraginpean dagoen lekuetan gertatzen da, baina beste leku batzuetan ere ager daiteke. BD normalean lesio bakar gisa agertzen da. BD sarritan abisu seinale gisa ikusten da azaleko minbizi mota larriagoa garatu aurretik. BD diagnostikatzeko, medikuek normalean ehun-laginak mikroskopioan (biopsia) aztertzean oinarritzen dira.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease 60 urtetik gorako pertsona zuriei eragiten die gehienbat. Arrisku-faktore nagusiak epe luzerako eguzki-esposizioa, sistema immunologikoa ahuldua, artseniko esposizioa eta larruazaleko HPV infekzioa dira. HPV 16, 18, 34 eta 48 anduiak Bowen-en gaixotasunarekin lotuta daude eremu genitaleetan. Genitalak ez diren kasuetan HPV-k duen inplikazioa ez da hain argia.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Normalean, gorputzeko edozein lekutan eritematoso, ezkatatsu edo lurrazaleko eremu gisa agertzen da. Kokapen ohikoena beheko hankak dira.
Hainbat tratamendu aukeren bidez senda daiteke, hala nola, krioterapia, curetatage, kauterizazioa, terapia fotodinamikoa edo lesioaren eszisioa.
○ Diagnostikoa eta Tratamendua
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy