Melasma
☆ Saksan vuoden 2022 Stiftung Warentest -tuloksissa kuluttajien tyytyväisyys ModelDermiin oli vain hieman alhaisempi kuin maksullisiin telelääketieteen konsultaatioihin.
Se on yleinen tila, jota havaitaan 40-vuotiailla aasialaisilla naisilla. Kuvan ympyröity vaurio on lähempänä lentigoa kuin melasmaa.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Viime aikoina low-fluence Q-switched Nd:YAG (LFQSNY) laserista on tullut suosittu melasman hoidossa, erityisesti Aasiassa. Erilaisten tutkimusten yhteenveto oli haastavaa, mutta LFQSNY vaikuttaa yleisesti tehokkaalta ja turvalliselta melasman hoidossa perinteisiin hoitoihin verrattuna. LFQSNY:n sivuvaikutuksena on kuitenkin raportoitu joissakin tapauksissa täpläistä hypopigmentaatiota, joka saattaa johtua korkeasta laserenergiasta. LFQSNY:n aggressiivinen käyttö voi myös johtaa tulehduksen aiheuttamaan hyperpigmentaatioon, erityisesti tummemmissa ihosävyissä.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentaatioongelmia löytyy usein perusterveydenhuollosta. Yleisiä hyperpigmentaatiohäiriötyyppejä ovat post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasmaa ei voida parantaa laserhoidolla tietyn ajan, koska se on sairaus, jossa pigmenttiä muodostuu jatkuvasti. Trankseneemihappo auttaa vähentämään pigmentaatiota.
○ Hoito
Joissakin maissa (esim. Japanissa, Koreassa) oraalista traneksaamihappoa on saatavana reseptivapaasti ja se on tehokasta. Melasma voide, jossa on traneksaamihappoa ja atselaiinihappoa, voi olla osittain hyödyllinen.
Hydrokinonia voidaan käyttää paikallisesti hyperpigmentaation hoitoon, mutta FDA lopetti hydrokinonia sisältävät OTC-tuotteet vuodesta 2020 alkaen.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma