Acute generalized exanthematous pustulosis - Akute Generalisearre Eksanthematous Pustulose
Akute Generalisearre Eksanthematous Pustulose (Acute generalized exanthematous pustulosis) (AGEP) is in seldsume hûdreaksje dy't yn 90% fan 'e gefallen relatearre is oan administraasje fan medisinen. akute generalisearre eksanthematous pustulose (acute generalized exanthematous pustulosis) wurdt karakterisearre troch hommels hûdútbarstings dy't yn trochsneed fiif dagen ferskine nei't in medikaasje is begon. Dizze útbarstings binne pustules, dus lytse reade wyt of reade útbarsting fan 'e hûd dy't bewolkt of purulent materiaal (pus) befetsje. De hûdlesjes ferdwine normaal binnen 1-3 dagen nei it stopjen fan 'e misledigjende medikaasje.
☆ Yn 'e 2022 Stiftung Warentest-resultaten út Dútslân wie de konsuminttefredenheid mei ModelDerm mar wat leger dan mei betelle telemedisynkonsultaasjes.
Wiidferspraat lesions mei erythema en pustules ferskine ynienen.
References
Acute generalized exanthematous pustulosis (AGEP) is in hûdreaksje markearre troch lytse, mei pus fol bulten op in reade hûdbasis. It bart normaal as immen bepaalde medisinen nimt, lykas antibiotika, en ferspriedt fluch oer it lichem. Nei it stopjen fan 'e triggerjende medikaasje geane de symptomen typysk binnen twa wiken fuort, faaks litte guon hûdferlies. Hoewol normaal net serieus en beheind ta de hûd, kinne slimme gefallen wurde klassifisearre neist oare serieuze hûdreaksjes lykas Stevens-Johnson syndrome of toxic epidermal necrolysis. Behanneling is foaral stypjende soarch, en de prognose foar folsleine resolúsje fan 'e sykte is meastal poerbêst.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Recent experimental data reviewed herein are supportive of an early role of drug-induced innate immune activation and innate cytokines such as interleukin (IL)-1, IL-36, and IL-17 in the pathogenesis of AGEP. This explains the rapid onset and neutrophilic character of the cutaneous inflammation.
In 76-jierrige man kaam op de meldkeamer om't syn hûd de ôfrûne twa dagen feroare wie. Dokters fûnen reade plakken en ferhege gebieten op syn romp en earms en skonken. Nei't de tiid trochgie, kamen dizze patches byinoar, en hy ûntwikkele puistje-achtige bulten yn 'e reade gebieten. Tests lieten hege wite bloedsellen sjen mei in protte fan in type neamd neutrophilen, en ferhege nivo's fan C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
