Drug eruption - Drugs Útbarsting
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Drugs Útbarsting (Drug eruption) wurdt karakterisearre troch it beynfloedzjen fan it hiele lichem.
References
Hûreaksjes feroarsake troch medikaasje, bekend as drugsútbarstings, kinne soms swier wêze. Dizze slimme reaksjes, neamd severe cutaneous adverse drug reactions (SCARs) , wurde as libbensbedreigend beskôge. Se befetsje betingsten lykas Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Wylst SCARs seldsum binne, ûnderfine sawat 2% fan sikehûspasjinten se.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
In 31-jierrige frou besocht de ôfdieling dermatology mei in pynleaze reade pleister boppe op har rjochterfoet. Se naam ien doasis doxycycline (100 mg) de dei derfoar, nei picosecond laser behanneling foar acne littekens. Ferline jier ûnderfûn se in ferlykber probleem op itselde plak nei it nimmen fan deselde dosis doxycycline post-laserbehanneling. Se hat gjin wichtige medyske skiednis en gjin oare symptomen, lykas koarts, lokaal of troch har lichem.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) en toxic epidermal necrolysis (TEN) binne twa foarmen fan in serieuze hûdreaksje, oars as oare hûdsomstannichheden lykas erythema multiforme major en staphylococcal scalded skin syndroom, lykas drugsreaksjes. SJS/TEN is in seldsume en slimme reaksje dy't wiidferspraat skea oan 'e hûd en slijmvliezen feroarsaket, faak mei systemyske symptomen. Yn mear as 80% fan 'e gefallen binne medisinen de oarsaak.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Drug-útbarstingen wurde benammen diagnostearre út 'e medyske skiednis en klinysk ûndersyk. In hûdbiopsy, bloedûndersiken of immunologyske tests kinne ek nuttich wêze.
Foarbylden fan mienskiplike medisinen dy't de útbarsting feroarsaakje binne antibiotika en oare antimikrobiële medisinen, sulfa-medisinen, nonsteroidale anty-inflammatoare medisinen (NSAID's), gemoterapy-aginten foar maligniteiten, anty-konvulsiva en psychotropyske medisinen.
○ Diagnose en behanneling
As jo koarts hawwe (ferhege lichemstemperatuer), moatte jo sa gau mooglik medyske oandacht sykje. De fertochte medisyn moat stopset wurde (bygelyks antibiotika, net-steroidale anty-inflammatoare medisinen). Foardat jo it sikehûs besykje, kinne orale antihistaminen lykas cetirizine of loratadine helpe foar jeuk en útslach.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Bloedtest (CBC, LFT, eosinophil count)
Orale steroïden en antihistaminen mei recept fan dokter