Herpes zoster
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Herpes zoster blieren op 'e nekke en skouder
relevance score : -100.0%
ReferencesShingles, feroarsake troch de reaktivearring fan it varicella zoster-firus ferantwurdlik foar wetterpokken, treft jierliks sawat 1 miljoen minsken yn 'e Feriene Steaten, mei in libbensrisiko fan 30%. Dy mei ferswakke immúnsysteem binne signifikant mear gefoelich foar it ûntwikkeljen fan gordelroas (shingles), mei symptomen dy’t typysk begjinne mei malaise, hoofdpijn, en in mylde koarts, folge troch ûngewoane hûdsensaasjes in pear dagen foar it ferskinen fan in útslach. Dizze útslach, dy’t meastentiids yn in spesifyk gebiet fan it lichem ferskynt, giet oer in wike oant tsien dagen troch fan dúdlike blieren nei krustige wûnen. Snelle behanneling mei antivirale medisinen (acyclovir, valacyclovir, of famciclovir) binnen 72 oeren nei útslach is krúsjaal. Postherpetyske neuralgie, in mienskiplike komplikaasje karakterisearre troch langere pine yn it troffen gebiet, beynfloedet sawat ien op fiif pasjinten en fereasket trochgeande behear mei medisinen lykas gabapentin, pregabalin, of bepaalde antidepresinten, tegearre mei topike aginten lykas lidocaine of capsaicin. Faksinaasje tsjin it varicella zoster-firus wurdt oanrikkemandearre foar folwoeksenen fan 50 jier en âlder om it risiko op gordelroas (shingles) te ferminderjen.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Herpes zoster hat de neiging faker foar te kommen by minsken fan 50 jier en âlder, dyjigen mei ferswakke immúnsysteem, en dyjigen dy't immunosuppressive medisinen nimme. It wurdt trigger troch de reactivation fan it varicella‑zoster virus, itselde virus dat chickenpox feroarsaket. Symptomen lykas fever, pain en itch geane gewoanlik foar it ferskinen fan de karakteristike rash. De meast foarkommende komplikasje is postherpetic neuralgia, dat is oanhâldende nerve pain neidat de rash ferdwynt. De risikofaktoaren en komplikasjes dy't ferbûn binne mei Herpes zoster fariearje ôfhinklik fan leeftyd, immúnsûnens, en timing fan inisjatyf fan behanneling. Vaccination foar yndividuen fan 60 jier en boppe is oantoand om it foarkommen fan Herpes zoster en postherpetic neuralgia signifikant te ferminderjen. Begjin fan antiviral medications en pain relievers binnen 72 oeren nei it begjin fan rash kin de earnst en komplikasjes fan Herpes zoster en postherpetic neuralgia ferminderje.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
De klinyske proeven foar goedkarring jouwe oan dat it live zoster vaccine (live zoster vaccine) sawat 50 oant 70 % wurket, wylst it recombinant vaccine (recombinant vaccine) better prestearret, fariearjend fan 90 oant 97 %. Yn echte wrâldstúdzjes stypje se de befinings fan 'e proeven, en litte sjen dat it live zoster vaccine (live zoster vaccine) sawat 46 % effektyf is, wylst de recombinant vaccine (recombinant vaccine) sawat 85 % is.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Waterpokken, ek wol varicella neamd, ûntstiet út 'e earste ynfeksje mei it virus, typysk foarkomt yn' e jeugd of adolesinsje. As de wetterpokken ienris genêzen is, kin it virus jierren of desennia ynaktyf (sliepend) bliuwe yn minsklike senuwsellen, wêrnei't it opnij aktivearje kin. Herpes zoster resultaat as it sliepende varicella virus wurdt reaktivearre. Dan reizget it virus lâns nerve‑lichems nei nerve‑einen yn 'e hûd, en produsearret blieren. Tidens in útbraak fan herpes zoster kin bleatstelling oan it varicella virus fûn yn herpes zoster blieren wetterpokken feroarsaakje by ien dy't noch gjin wetterpokken hân hat.
Risikofaktoaren foar reaktivaasje fan it sliepende virus omfetsje âlderdom, minne ymmúnfunksje, en it hawwen fan wetterpokken foar 18 moannen âld. varicella‑zoster virus is net itselde as herpes simplex virus, hoewol beide hearre ta deselde famylje fan herpesviruses.
Herpes zoster faksinen ferminderje it risiko fan herpes zoster mei 50 % oant 90 %. It fermindert ek tariven fan postherpetyske neuralgie, en, as herpes zoster optreedt, de earnst dêrfan. As herpes zoster ûntwikkelet, kinne antivirale medisinen lykas aciclovir de earnst en doer fan 'e sykte ferminderje as binnen 72 oeren nei it ferskinen fan' e útslach begon.
○ Behanneling
As de lesions rap ferspriede, sjoch jo dokter sa gau mooglik foar antivirale behanneling.
Sawol antivirale medisinen as neuralgie‑medikaasjes binne ferplicht. Jo moatte rêste en stopje mei it drinken fan alkohol.
#Acyclovir
#famciclovir
#Valacyclovir
#Gabapentin
#Pregabalin
#Acyclovir
#Fancyclovir
#Valacyclovir
#Gabapentin
#Pregabalin