Poikiloderma
Poikiloderma is in hûdsyndroom dy't bestiet út gebieten fan hypopigmentaasje, hyperpigmentaasje, telangiektasias en atrofye. Poikiloderma wurdt it meast sjoen op de boarst of hals, karakterisearre troch readkleurige pigment op de hûd dy't gewoanlik ferbûn is mei sinneskade.
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ReferencesPoikiloderma of Civatte is in benigne hûdbetingst dy’t benammen op ’e nek en it gesicht ferskynt, fral by froulju mei ljochte hûd, postmenopausale. It toant as in kombinaasje fan in retikuleair patroan fan lineêre telangiectasies, fleckige hyperpigmentaasje en oppervlakkige atrofie. Typysk beynfloedet it symmetrisch sonbloate gebieten, lykas it gesicht, de nek en it V‑vormige boarstgebiet, en spytet de skaduwearde gebieten. Poikiloderma of Civatte kin wurde klassifisearre op basis fan syn klinyske typen: erythemato‑telangiectatysk, pigmentear, en gemixe type. De krekte oarsaak is net folslein begrepen, mar faktoaren lykas ultraviolette strieling, hormonale feroaringen fan de menopouse, kontakt‑sensitisaasje foar parfums en kosmetika, en normale aldrichheid wurde yn in rol besjoen. Poikiloderma of Civatte hat de neiging om stadichoan progresyf en onomkeerbaar te wêzen, faak leidend ta merkbare kosmetyske ferwoarring.
Poikiloderma of Civatte (PC) is a rather common benign dermatosis of the neck and face, mainly affecting fair-skinned individuals, especially postmenopausal females. It is characterized by a combination of a reticular pattern of linear telangiectasia, mottled hyperpigmentation and superficial atrophy. Clinically, it involves symmetrically sun-exposed areas of the face, the neck, and the V-shaped area of the chest, invariably sparing the anatomically shaded areas. Depending on the prevalent clinical feature, PC can be classified into erythemato-telangiectatic, pigmented, and mixed clinical types. The etiopathogenesis of PC is incompletely understood. Exposure to ultraviolet radiation, hormonal changes of menopause, contact sensitization to perfumes and cosmetics, and normal ageing have been incriminated. The diagnosis is usually clinical and can be confirmed by histology, which is characteristic, but not pathognomonic. The course is slowly progressive and irreversible, often causing significant cosmetic disfigurement.
Poikiloderma of Civatte (PC) is a rather common benign dermatosis of the neck and face, mainly affecting fair-skinned individuals, especially postmenopausal females. It is characterized by a combination of a reticular pattern of linear telangiectasia, mottled hyperpigmentation and superficial atrophy. Clinically, it involves symmetrically sun-exposed areas of the face, the neck, and the V-shaped area of the chest, invariably sparing the anatomically shaded areas. Depending on the prevalent clinical feature, PC can be classified into erythemato-telangiectatic, pigmented, and mixed clinical types. The etiopathogenesis of PC is incompletely understood. Exposure to ultraviolet radiation, hormonal changes of menopause, contact sensitization to perfumes and cosmetics, and normal ageing have been incriminated. The diagnosis is usually clinical and can be confirmed by histology, which is characteristic, but not pathognomonic. The course is slowly progressive and irreversible, often causing significant cosmetic disfigurement.
