Prurigo nodularis
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References
Prurigo nodularis is in langduorjende hûdbetingsten karakterisearre troch meardere stevige bulten en nodules, meast te finen op 'e bûtenste dielen fan' e earms en skonken. Dizze bulten kinne fariearje yn kleur fan fleis-toned oant roze en binne yntinsyf jeukende. Se kinne minsken fan elke leeftyd beynfloedzje en wurde faak keppele oan oare hûdomstannichheden dy't chronike jeuk feroarsaakje, lykas atopyske dermatitis. Behanneling opsjes omfetsje sterke anty-jeuk medisinen, medisinen dy't ynfloed op it ymmúnsysteem, en medisinen dy't rjochtsje op it senuwstelsel. It behearjen fan de prurigo nodularis omfettet meastentiids lange termyn terapy.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Behanneling omfettet normaal gebrûk fan crèmes as ynjeksjes fan steroïden op it troffen gebiet. Yn slimmer of eigensinnige gefallen kinne behannelingen lykas ljochtterapy of medisinen nedich wêze dy't it ymmúnsysteem ûnderdrukke. Thalidomide en lenalidomide binne opsjes foar swiere gefallen, mar se kinne serieuze side-effekten hawwe. Nijere behannelingen (opioid receptor antagonists, neurokinin-1 receptor antagonists) litte belofte sjen yn it behanneljen fan prurigo nodularis mei minder side-effekten yn ferliking mei thalidomide of lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo is in hûdbetingsten karakterisearre troch langdurige jeuk (duorje mear dan 6 wiken) , krassen-relatearre hûdlesjes, en in skiednis fan faak krassen. It giet om neuroinflammaasje en fibrosis yn 'e hûd.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis is in lang duorjend hûdprobleem markearre troch jeukende nodules. Wy witte net krekt wat it feroarsaket, mar it liket derop dat ymmún- en nerveproblemen in rol spylje yn 'e jeuk-krassyklus. Op it stuit binne d'r gjin behannelingen goedkard troch de US FDA spesifyk foar prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Behanneling ― OTC Drugs
It lijengebiet waskje mei sjippe helpt hielendal net en kin it slimmer meitsje. OTC-steroïde salven kinne helpe om de symptomen te ferminderjen, mar se moatte normaal ferskate wiken tapast wurde om te ferbetterjen. Trochgean mei it nimmen fan antihistaminen helpt ek de jeuk te ferminderjen.
#OTC steroid ointment
#OTC antihistamine
○ Behanneling
#Intralesional triamcinolone injection