Acanthosis nigricanshttps://en.wikipedia.org/wiki/Acanthosis_nigricans
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Molaíonn pigmentation dubh agus roic sa dá armpits Acanthosis nigricans.
relevance score : -100.0%
References Acanthosis Nigricans 28613711 NIH
Is léiriú cutaneous de riocht bunúsach é Acanthosis nigricans. Is minic a bhíonn sé le feiceáil i bhfillteacha craiceann cosúil leis an muineál, an armpits, agus an groin, cosúil le paistí dorcha velvety le imill doiléir. Tá an coinníoll seo nasctha de ghnáth le diaibéiteas agus friotaíocht inslin, ach i gcásanna neamhchoitianta, d'fhéadfadh sé pointe a ailse taobh istigh den chorp. D'fhéadfadh sé a thaispeáint suas freisin mar gheall ar shaincheisteanna hormóin nó ó ghlacadh míochainí ar leith cosúil le stéaróidigh agus pills rialú breithe.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Current treatment options for acanthosis nigricans 30122971 NIH
Is riocht craiceann coitianta é Acanthosis nigricans (AN) atá nasctha le saincheisteanna sláinte éagsúla cosúil le frithsheasmhacht in aghaidh inslin, diaibéiteas, murtall, ailsí áirithe, fadhbanna hormónacha, agus frithghníomhartha ar chógais. Díríonn cóireáil AN ar aghaidh a thabhairt ar na bunfhadhbanna sláinte. Ar dtús, déanann dochtúirí seiceáil le haghaidh comharthaí de shiondróm friotaíochta insulin, lena n-áirítear otracht, colaistéaról ard, brú fola ard, agus diaibéiteas cineál 2. Is minic a fhorordaíonn dochtúirí topical retinoids mar an chéad rogha cóireála, rud a d'fhéadfadh cabhrú le ramhrú craiceann. Mar sin féin, ní fhéadfaidh siad dul i ngleic go hiomlán le dorchadas craiceann. Ní mór roghanna cóireála eile (salicylic acid, podophyllin, urea, calcipotriol) a chur i bhfeidhm go minic freisin.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Cúis
Tarlaíonn sé go hiondúil i ndaoine níos óige ná 40 bliain d’aois, d’fhéadfadh sé a bheith le hoidhreacht ghéiniteach agus tá baint aige le murtall nó inchrínopaití, mar hipthíoróideacht, acromegaly, galar ubhagán polycystic, diaibéiteas resistant insulin nó galar Cushing.
○ Cóireáil - Drugaí OTC
#40% urea cream