Tuilleadh eolais ― Gaeilge

Tháinig bean 26 bliain d'aois chuig ár gclinic ag gearán faoi ghríos totach ar a cosa a bhí aici le 10 mbliana. In ainneoin uachtair stéaróideacha agus uachtar tazarotene a úsáid, níor éirigh an gríos níos fearr. Ní raibh aon stair teaghlaigh ábhartha aici. Nuair a scrúdaíomar í, fuaireamar paistí ardaithe, garbha ar thaobh tosaigh a cosa, rud a mheaitseálann galar ar a dtugtar lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Is riocht annamh craicinn é Lichen Amyloidosis a bhaineann le tochas leanúnach gan chúis anaithnid. De ghnáth taispeánann sé suas mar bhraislí de phaistí ardaithe, mídhaite ar dhromchlaí seachtracha an chraiceann. De ghnáth bíonn Lichen Amyloidosis le feiceáil i ndaoine idir 50 agus 60 bliain d’aois agus ar an drochuair, níl aon leigheas air. De ghnáth ní oibríonn na cóireálacha atá ar fáil anois go maith.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Is riocht craiceann itchy é Lichen amyloidosis. Is eol dó braislí de chnapóga tiubhaithe a fhaightear go príomha ar chúl, ar shins, ar thighs agus ar airm. Nuair a dhéantar é a scrúdú faoi mhicreascóp, taispeánann Lichen amyloidosis tógáil amyloid sa chiseal barr craiceann mar aon le ramhrú agus méadú ar chiseal seachtrach an chraiceann. Cé nach dtuigtear cúis bheacht Lichen amyloidosis go hiomlán fós, cheangail staidéir roimhe seo é le fachtóirí mar chuimilt nó cuimilte ar an gcraiceann, bás cille, ionfhabhtuithe víreasacha, i measc nithe eile. Is cosúil go bhfuil Lichen amyloidosis nasctha le roinnt riochtaí craicinn eile (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.