Dysplastic nevus - Nevus Dysplastic
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Dysplastic nevi – Moltar bithóipse do mhuintir an Iarthair.
relevance score : -100.0%
ReferencesTá Dysplastic nevus, ar a dtugtar nevus aitíopúla nó Clarks freisin, tar éis díospóireachtaí i dermaíolaíocht a spreagadh. Is minic a dhéanfann dochtúirí bithóipéise de na mól seo toisc go mbíonn cuma neamhghnách orthu agus go n-ardaíonn siad imní maidir le melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi, ar a dtugtar aitíopúla nó Clark nevi freisin, is féidir meileanóma a bheith mar thoradh air uaireanta. Faightear thart ar 36 % de melanomas i ngar don dysplastic nevi. I measc na gcomharthaí a d’fhéadfadh go n-iompódh nevus dysplastic ina melanoma tá cruth míchothrom, athruithe móra ar na líochana, nó dath liathghlas. Tarlaíonn na hailse seo de ghnáth ag aois níos óige (thart ar lár na dtríochaidí), is féidir leo a bheith iolrach, agus is minic a bhíonn siad ar an stoc. Go géiniteach, tá dysplastic nevi idir nevi neamhurchóideach agus meileanóma. Mar sin féin, ní thagann ach 20 % go 30 % de melanomas ó nevi atá ann cheana féin. Ós rud é nach n-éiríonn melanóma ar bhformhór na nevi, de ghnáth ní mholtar iad a bhaint go coisctheach.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Is cineál ailse é melanoma a fhoirmíonn nuair a éiríonn melanocytes, cealla atá freagrach as dath an chraiceann, ailse. Tagann melanocytes ó shúitheantas néarúil. Ciallaíonn sé seo gur féidir le melanomas forbairt ní hamháin ar an gcraiceann ach freisin i réimsí eile ina n-imíonn cealla néaracha suaitheantais, cosúil leis an gcolainn gastrointestinal agus an inchinn. Tá an ráta mairbhithe d’othair a bhfuil melanoma luathchéime acu (céim 0) ard ag 97%, agus titeann sé go suntasach go dtí thart ar 10% dóibh siúd a diagnóisíodh le galar ardchéime (céim IV).
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ príacal ailse
Mar a fheictear i ndéantóirí Caucasian sna Stáit Aontaithe, tá riosca saoil níos mó ná 10 % acu siúd a bhfuil dysplastic nevi orthu, ag fhorbairt melanoma. Ar an láimh eile, tá baol níos lú ná 1 % acu siúd nach bhfuil aon nevi dysplastic acu, ag fhorbairt melanoma.
○ Réamhchúram do dhaoine aonair a bhfuil dysplastic nevi acu
De ghnáth moltar féinscrúdú craiceann chun melanoma a chosc (trí nevi aitíopúla a bhaint) nó le haghaidh na n‑ádhanna atá ann cheana féin a bhrath go luath. Ba chóir do dhaoine a bhfuil stair phearsanta nó teaghlaigh acu le hailse craicinn nó nevi aitíopúla iolra, deirmeolaí a fheiceáil uair sa bhliain ar a laghad, chun a bheith cinnte nach bhfuil melanoma á fhorbairt acu.
Bhí an giorrúchán [ABCDE] úsáideach chun cabhrú le soláthraithe cúraim sláinte agus le daoine cuimhneamh ar phríomhthréithe melanoma. Ar an drochuair, d’fhéadfadh go mbeadh tréithe [ABCDE] i go leor keratoses seborrheic, i roinnt lentigo sénile, agus fiú i warts, agus ní féidir iad a idirdhealú ó melanoma.
○ [ABCDE]
Asymmetrical: léas craiceann neamhshiméadrach.
Border: tá teorainn an léasa neamhrialta.
Color: is gnách go mbíonn dathanna neamhrialta iolracha ag melanomas.
Diameter: tá sé níos dócha go mbeadh melanomas i nevi níos mó ná 6 mm ná i nevi níos lú.
Evolution: féadfaidh éabhlóid (i.e. athrú) nevi nó lot a léiriú go bhfuil an lot ag éirí urchóideach.