Panniculitis
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Tá eitinn ar cheann de na cúiseanna suntasacha.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis foirm ghrúpa ilchineálach de ghalair athlastacha a bhaineann leis an bhfíochán saille subcutaneous. Is annamh a bhíonn na neamhoird seo i leanaí. Is féidir leis an panniculitis a bheith ar an bpróiseas príomhúil i neamhord sistéamach nó próiseas tánaisteach a eascraíonn as ionfhabhtú, tráma nó nochtadh do chógas. Tá an cur i láthair cliniciúil céanna ag formhór na panniculitis (beag beann ar an aetiology) , le nodules tairisceana, erythematous subcutaneous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , athlasadh na subcutaneous saille, i láthair de ghnáth le nodules athlastacha. Is é Erythema nodosum (EN) an cineál panniculitis is minice go cliniciúil. Cé go meastar go bhfuil suas le 55% de EN idiopathic, áirítear ar na cúiseanna is coitianta ionfhabhtuithe, drugaí, tinnis sistéamach mar sarcoidosis agus galar putóige athlastach, toircheas, agus urchóideacht. Tagann EN i láthair go hiondúil sna déagóirí agus sna 20idí, agus feictear é níos coitianta i measc baineannaigh. Is minic a thagann pródróm neamhshonrach de sheachtain amháin nó trí seachtaine roimhe sin, a d’fhéadfadh fiabhras, malaise, agus comharthaí ionfhabhtaithe sa chonair riospráide uachtarach a áireamh. Leanann loit sceana ansin, go hiondúil logánta ar thaobh na géaga de shíneadh. Tá na loit pianmhar chothromú nó ubhchruthach, nodules dearga neamh-ulcerative beagán ardaithe. Ní thuigtear pataigineas beacht EN, cé go gceaptar go bhfuil sé mar thoradh ar choimpléisc imdhíonachta a bheith curtha i venules na septae i saill fhochraicneach, rud is cúis le panniculitis neodrófilic. Fiú gan teiripe ar leith do riocht cúiseach, réitíonn EN gan chóireáil i bhformhór na gcásanna.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Is cineál panniculitis é "Erythema nodosum" arb iad is sainairíonna é nódúil dhearga tairisceana, 1-10 cm, a bhaineann le hairíonna sistéamacha lena n-áirítear fiabhras, malaise, agus pian sna hailt. Féadfaidh nodules subside thar thréimhse 2-6 seachtaine gan ulcerating nó scarring. Tá baint ag erythema nodosum le hionfhabhtuithe, lena n-áirítear Heipitíteas C, EBV agus eitinn, toircheas, liomfóma Neamh-Hodgkin, agus ailse pancreatach.