Staphylococcal scalded skin syndrome - Siondróm Craiceann Scaldáilte Staphylococcal
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Naíonán le Siondróm Craiceann Scaldáilte Staphylococcal (Staphylococcal scalded skin syndrome)
References
Is coinníoll é Staphylococcal Scalded Skin Syndrome ina n-ídíonn an craiceann de bharr tocsainí arna dtáirgeadh ag cineálacha áirithe baictéir Staphylococcus. Tá sé neamhchoitianta i leanaí os cionn sé bliana d'aois. Is féidir leis tarlú freisin i ndaoine fásta a bhfuil córais imdhíonachta lagaithe nó fadhbanna duáin tromchúiseacha acu. Is í an phríomhghné feannadh craiceann fairsing tar éis athlasadh. Réimsíonn déine ó roinnt blisters go caillteanas craiceann forleathan, rud a d'fhéadfadh titim mhór i dteocht an choirp agus éagobhsaíocht brú fola a chur faoi deara.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Tháinig buachaill 10 mí d'aois isteach le srón runny agus ní raibh sé ag ithe go maith. Dúirt dochtúirí gur ionfhabhtú riospráide uachtarach a bhí ann. Dhá lá ina dhiaidh sin, tháinig sé ar ais mar ní raibh sé ag éirí níos fearr agus bhí fadhbanna nua aige mar aghaidh ata agus craiceann irritated timpeall an bhéil. Thar an dá lá ina dhiaidh sin, d'éirigh an buachaill níos measa. D'ardaigh a lámha agus a chosa agus thosaigh a chraiceann ag titim amach. Ar ais ag an ospidéal, thug na dochtúirí gríos dearg ar a aghaidh agus i bpill a chraiceann, a blanched nuair a bhíothas i dteagmháil léi. Rinne siad staphylococcal scalded skin syndrome (SSSS) a dhiagnóisiú agus thosaigh siad ar antaibheathaigh trí vein.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
Thaispeáin cailín 2 bhliain d'aois suas le gríos ar fud a colainne a d'fhorbair thar 48 uair an chloig, tar éis biteanna feithidí ar a héadan an lá roimhe sin. Le linn an scrúdaithe, bhí gríos forleathan uirthi déanta suas de chnaipí beaga a tháinig le chéile, agus nuair a chuimil sé go héadrom, léirigh a craiceann comharthaí Nikolsky. Ní raibh aon chomharthaí ann go raibh an gríos ag cur isteach ar a seicní múcasacha. Níor léirigh tástálacha ar a cuid fola aon chomharthaí ionfhabhtaithe.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
Cothaítear an siondróm ag exotoxins epidermolytic (exfoliatin)A agus B, a scaoileann S. aureus. Tá an prognóis siondróm craiceann scaldáilte staphylococcal (staphylococcal scalded skin syndrome) i leanaí den scoth, le réiteach iomlán laistigh de 10 lá tar éis cóireála, agus gan scarring suntasach. Mar sin féin, ní mór siondróm craiceann scaldáilte staphylococcal (staphylococcal scalded skin syndrome) a dhifreáil go cúramach ó necrolysis epidermal tocsaineach, a iompraíonn droch-prognóis.
○ Diagnóis agus Cóireáil
Méadaíonn mídhiagnóis mar loit eachma amhail dheirmitíteas atópach, agus ointment steroid a chur i bhfeidhm. Iarr cúram leighis chomh luath agus is féidir agus ointment antaibheathach á úsáid agat.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)