Tuilleadh fiosrachaidh ― Scots gaelic

Thàinig boireannach 26-bliadhna chun chlinic againn a’ gearan mu dheidhinn broth tachaiseach air a casan a bha i air a bhith airson 10 bliadhna. A dh 'aindeoin a bhith a' cleachdadh uachdaran steroid agus uachdar tazarotene, cha do dh'fhàs am broth na b 'fheàrr. Cha robh eachdraidh teaghlaich iomchaidh sam bith aice. Nuair a rinn sinn sgrùdadh oirre, lorg sinn badan àrda, garbh air beulaibh a casan, a bha a rèir galar ris an canar lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Is e suidheachadh craiceann tearc a th’ ann an Lichen Amyloidosis co-cheangailte ri itching leantainneach gun adhbhar neo-aithnichte. Mar as trice bidh e a’ nochdadh mar chlàran de phìosan àrdaichte, dathach air uachdar a-muigh a’ chraicinn. Mar as trice bidh Lichen Amyloidosis a’ nochdadh ann an daoine aois 50 gu 60 agus gu mì-fhortanach, chan eil leigheas ann air a shon. Mar as trice chan eil làimhseachadh a tha ri fhaighinn an-dràsta ag obair gu math.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Tha Lichen amyloidosis na staid itchy craiceann fad-ùine. Tha e ainmeil airson cruinneachaidhean de chnapan tiugh a lorgar sa mhòr-chuid air a’ chùl, shins, sliasaid, agus gàirdeanan. Nuair a thèid a sgrùdadh fo mhiocroscop, tha Lichen amyloidosis a’ sealltainn cruinneachadh de amyloid anns an t-sreath as àirde den chraiceann còmhla ri tiugh agus leudachadh air còmhdach a’ chraicinn a-muigh. Ged nach eilear a’ tuigsinn fìor adhbhar Lichen amyloidosis fhathast, tha sgrùdaidhean roimhe air a cheangal ri factaran mar suathadh no suathadh air a’ chraiceann, bàs cealla, galairean viral, am measg feadhainn eile. Tha e coltach gu bheil Lichen amyloidosis ceangailte ri grunn shuidheachaidhean craiceann eile (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.