Amyloidosis https://en.wikipedia.org/wiki/Amyloidosis
https://en.wikipedia.org/wiki/Amyloidosis
☆ AI Dermatology — Free ServiceAnn an toraidhean 2022 Stiftung Warentest às a’ Ghearmailt, cha robh sàsachd luchd-cleachdaidh le ModelDerm ach beagan nas ìsle na le co-chomhairlean telemedicine pàighte.   - Feartan aghaidh clasaigeach de Amyloidosis 
 - Anns an t-sealladh meudaichte, thathas a’ cumail sùil air papules cruaidh le cumadh coltach ris. Tha iad an ìre mhath èileadh agus cruaidh, eu-coltach ri eas-òrdughan aileintich leithid atopic dermatitis. 
  - Feartan craiceann de amyloidosis cutis dyschromica ― (A) Macules hyperpigmented agus hypopigmented air a’ chas ìosal 
 - Lichen amyloidosis gu tric air a mhì-bhreithneachadh mar dermaitis atopic (atopic dermatitis). Tha cùis àbhaisteach a’ nochdadh le papailean beaga cruaidh agus pruineadh (itching). 
 - Is dòcha gu bheil an lesan Amyloidosis coltach ri atopic dermatitis. 
relevance score : -100.0%
References Lichen amyloidosis - Case reports 24130236
 Lichen amyloidosis - Case reports 24130236 NIH
Thàinig boireannach 26-bliadhna chun clìneig againn a’ gearan mu dheidhinn broth sgeòrach (itchy rash) air a casan a bha i air a bhith airson 10 bliadhna. A dh’aindeoin a bhith a’ cleachdadh topical steroids agus tazarotene cream, cha do dh’fhuair am brodadh leigheas. Cha robh eachdraidh teaghlaich iomchaidh sam bith aice. Nuair a rinn sinn sgrùdadh oirre, lorg sinn hyperkeratotic papules garbh air beulaibh a casan, a bha a rèir ghalair ris an canar lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
 Lichen Amyloidosis: Towards Pathogenesis-Driven Targeted Treatment 36763750
 Lichen Amyloidosis: Towards Pathogenesis-Driven Targeted Treatment 36763750 NIH
Is e suidheachadh craiceann tearc a th’ ann an Lichen Amyloidosis co-cheangailte ri itching leantainneach gun adhbhar neo-aithnichte. Mar as trice bidh e a’ nochdadh mar chlàran de phìosan àrdaichte, dathach air uachdar a-muigh a’ chraicinn. Mar as trice bidh Lichen Amyloidosis a’ nochdadh ann an daoine aois 50 gu 60 agus gu mì-fhortanach, chan eil leigheas ann air a shon. Mar as trice chan eil làimhseachadh a tha ri fhaighinn an-dràsta ag obair gu math.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
 Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study 38086357
 Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study 38086357 NIH
Tha Lichen amyloidosis na staid itchy craiceann fad-ùine. Tha e ainmeil airson cruinneachaidhean de chnapan tiugh a lorgar sa mhòr-chuid air a’ chùl, shins, sliasaid, agus gàirdeanan. Nuair a thèid a sgrùdadh fo mhiocroscop, tha Lichen amyloidosis a’ sealltainn cruinneachadh de amyloid anns an t-sreath as àirde den chraiceann còmhla ri tiugh agus leudachadh air còmhdach a’ chraicinn a-muigh. Ged nach eilear a’ tuigsinn fìor adhbhar Lichen amyloidosis fhathast, tha sgrùdaidhean roimhe air a cheangal ri factaran mar suathadh no suathadh air a’ chraiceann, bàs cealla, galailean viral, am measg feadhainn eile. Tha e coltach gu bheil Lichen amyloidosis ceangailte ri grunn shuidheachaidhean craiceann eile (atopic dermatitis, lichen planus, mycosis fungoides).
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
 
○ Diagnosis agus Làimhseachan
#Electrophoresis of blood or urine
#Skin biopsy