Keloid
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Ann an toraidhean 2022 Stiftung Warentest às a’ Ghearmailt, cha robh sàsachd luchd-cleachdaidh le ModelDerm ach beagan nas ìsle na le co-chomhairlean telemedicine pàighte.
Ann an toraidhean 2022 Stiftung Warentest às a’ Ghearmailt, cha robh sàsachd luchd-cleachdaidh le ModelDerm ach beagan nas ìsle na le co-chomhairlean telemedicine pàighte.
keloid postoperative air an dùirn a chaidh a làimhseachadh le in-stealladh intralesional triamcinolone. Is e an raon erythema fodha air an taobh chlì an raon làimhseachaidh.
Linear Keloids. Nuair a bhios iad a ‘tachairt air aghaidh àrd an torso, bidh iad gu tric a’ nochdadh ann an cruth sreathach.
Posterior auricular Keloid
Faodaidh Keloids air buinn nan casan a bhith mì-chofhurtail coiseachd air. Mar as trice bidh in-stealladh steroid intralesional air a dhèanamh grunn thursan.
Tha Keloids gu tric rim faicinn air na gàirdeanan àrda.
Taisbeanadh àbhaisteach de keloids broilleach.
relevance score : -100.0%
ReferencesBidh keloids a’ cruthachadh mar thoradh air slànachadh neo-àbhaisteach às deidh dochann craiceann no sèid. Bidh factaran ginteil agus àrainneachd a’ cur ri an leasachadh, le ìrean nas àirde ann an daoine le craiceann nas dorcha de shliochd Afraganach, Àisianach agus Hispanic. Bidh Keloids a’ tachairt nuair a dh’ fhàsas fibroblasts ro‑ghnìomhach, a’ toirt a-mach cus collagen agus factaran fàis. Bidh seo a’ leantainn gu cruthachadh phasganan keloidal collagen, neo-àbhaisteach ris an canar collagen keloidal, còmhla ri àrdachadh ann am fibroblasts. Gu clionaigeach, tha keloids a ’nochdadh mar nodules làidir, rubair ann an ceàrnaidhean a chaidh a leòn roimhe. Eu‑coltach ri sgaraidhean àbhaisteach, tha keloids a ’leudachadh nas fhaide na an làrach trauma tùsail. Faodaidh euslaintich pian, itching, no losgadh fhaighinn. Tha diofar leigheasan rim faighinn, a’ gabhail a-steach in‑stealladh steroid, cryotherapy, lannsaireachd, radiotherapy, agus leigheas laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Tha an rannsachadh gnàthach a’ moladh gur e silicone gel no silicone sheeting còmhla ri in‑stealladh corticosteroid an làimhseachadh tùsail as fheàrr leotha airson keloids. Faodar beachdachadh cuideachd air leigheasan a bharrachd leithid 5‑fluorouracil intralesional (5‑FU), bleomycin, no verapamil, ged a tha an èifeachdas ag atharrachadh. Faodaidh leigheas laser, nuair a thèid a chur còmhla ri in‑stealladh corticosteroid no steroids gnàthach fo occlusion, cur ri dol a-steach dhrogaichean. Airson recalcitrant keloids, tha toirt air falbh lannsa air a leantainn le radiation therapy sa bhad air dearbhadh gu bheil e èifeachdach. Mu dheireadh, thathas air dearbhadh gu bheil cleachdadh silicone sheeting agus pressure therapy a ’lughdachadh an coltas gum bi keloid a’ tachairt a‑rithist.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
An-dràsta, chan eil làimhseachadh aon-mheud ann a tha a’ gealltainn ìre ath-chuairteachaidh cunbhalach ìosal airson keloids. Ach, tha na roghainnean a tha a’ fàs, leithid a bhith a’ cleachdadh lasers còmhla ri steroids no a’ cothlamadh 5-fluorouracil le steroids, gealltanach. Dh'fhaodadh rannsachadh san àm ri teachd fòcas a chuir air dè cho math 'sa tha leigheasan ùra, leithid grafadh geir fèin-fhillte no leigheasan stèidhichte air bun-cheallan, ag obair airson a bhith a' stiùireadh keloids.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Tha keloid mar phàirt cumanta den phròiseas slànachaidh às deidh leòn craiceann. Gu h-iomchaidh, bu chòir keloid a bhith firm, rubbery, agus a 'shiny dath a' chraicinn. Faodaidh mòran fhactaran leantainn gu droch slànachadh lotan, leithid gabhaltachd, sruth fala nas lugha, ischemia, agus trauma. Faodaidh keloid a tha hard, darker na an craiceann mun cuairt orra, no a tha a’ contracting cus, duilgheadasan mòra adhbhrachadh le gnìomhachd corporra agus slàinte thòcail.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Tha sgaraidhean keloid rim faicinn nas trice ann an daoine de shliochd Afraganach, Àisianach no Hispanic. Tha daoine eadar aois 10 agus 30 bliadhna nas buailtiche keloid a leasachadh na seann daoine.
Ged a bhios iad mar as trice a ’tachairt aig làrach leòn, faodaidh keloid èirigh gu neo‑eisimeileach cuideachd. Faodaidh iad tachairt aig làrach tolladh agus eadhon bho rudeigin cho sìmplidh ri pimple no scratch. Faodaidh iad tachairt mar thoradh air severe acne no scarring from chickenpox, infection at wound site, repeated trauma to an area, excessive skin tension during wound closure, or a foreign body in a wound.
Faodaidh sgaraidhean keloid leasachadh às deidh surgery. Tha iad nas cumanta ann an cuid de làraich, leithid central chest (bho sternotomy), back and shoulders (mar as trice mar thoradh air acne), agus ear lobes (bho ear piercings). Faodaidh iad cuideachd tachairt air other body piercings. Is e na spotan as cumanta ear lobes, arms, pelvic region, agus thairis air collarbone.
Is e na leigheasan a tha rim faighinn pressure therapy, silicone gel sheeting, triamcinolone acetonide intralesional, cryosurgery, radiation, laser therapy, Interferon, 5‑FU agus surgical excision.
○ làimhseachadh
Faodaidh hypertrophic scars leasachadh le 5 gu 10 intralesional steroid injections aig eadar-ama mìosail.
#Triamcinolone intralesional injection
Faodar làimhseachadh laser fheuchainn airson erythema co‑cheangailte ri scarring, ach faodaidh intralesional triamcinolone injection an erythema a leasachadh le bhith a’ rèidh a’ scar.
#Dye laser (e.g. V-beam)