Melasma
https://en.wikipedia.org/wiki/Melasma
☆ Ann an toraidhean 2022 Stiftung Warentest às a’ Ghearmailt, cha robh sàsachd luchd-cleachdaidh le ModelDerm ach beagan nas ìsle na le co-chomhairlean telemedicine pàighte. 

Is e suidheachadh cumanta a th’ ann am boireannaich Àisianach tràth anns na 40n. Tha an lesion cearcallach san dealbh nas fhaisge air lentigo seach melasma.
relevance score : -100.0%
References
Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 NIH
O chionn ghoirid, tha fèill mhòr air laser low-fluence Q-switched Nd:YAG (LFQSNY) airson a bhith a’ làimhseachadh melasma, gu sònraichte ann an Àisia. Bha e dùbhlanach a bhith a’ toirt geàrr-chunntas air sgrùdaidhean eadar-mheasgte, ach tha coltas gu bheil LFQSNY sa chumantas èifeachdach agus sàbhailte airson melasma an taca ri leigheasan traidiseanta. Ach, chaidh aithris a thoirt air cuid de chùisean de hypopigmentation mottled mar taobh-buaidh de LFQSNY, is dòcha mar thoradh air lùth laser àrd. Faodaidh cleachdadh ionnsaigheach de LFQSNY cuideachd leantainn gu hyperpigmentation bho shèid, gu sònraichte ann an tònaichean craiceann nas dorcha.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentation Disorders: Diagnosis and Management 29431372Gu tric lorgar duilgheadasan pigmentation ann an cùram bun-sgoile. Am measg nan seòrsaichean cumanta de dhuilgheadasan hyperpigmentation tha post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Chan urrainnear melasma a rèiteachadh le làimhseachadh laser airson ùine sònraichte, oir is e galar a th ’ann anns a bheil pigment air a thoirt a-mach gu leantainneach. Bidh searbhag tranxenemic a’ cuideachadh le bhith a’ lughdachadh pigmentation.
○ làimhseachadh
Ann an cuid de dhùthchannan (me Iapan, Korea), tha searbhag tranexamic beòil ri fhaighinn thairis air a’ chunntair agus tha e èifeachdach. Is dòcha gum bi an uachdar melasma le searbhag tranexamic agus searbhag azelaic gu ìre cuideachail.
Faodar hydroquinone a chleachdadh gu h-àrd airson làimhseachadh hyperpigmentation, ach chuir an FDA stad air toraidhean OTC anns an robh hydroquinone bho 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma