Syphilis - Sifilis
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Chancres ― prìomh ghalair syphilitic le Treponema pallidum
References
Is e galar gnèitheach a th’ ann an sifilis air adhbhrachadh leis a’ bacterium Treponema pallidum. Anns an sgrùdadh seo, bidh sinn a’ cuimseachadh air euslaintich 57 aois 18-68 le syphilis àrd-sgoile.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Tha syphilis na ghalar bactaraidh air adhbhrachadh le Treponema pallidum. Faodaidh e atharrais air diofar ghalaran, a’ cosnadh am far-ainm great imitator dha. Bidh sifilis fhathast a’ toirt buaidh air milleanan air feadh na cruinne ach faodar a làimhseachadh gu h-èifeachdach le penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Bidh Treponema pallidum ag adhbhrachadh sifilis tro cheangal gnèitheasach no bho mhàthair gu pàisde fhad ‘s a tha thu trom. Eadhon ged a tha deuchainnean sìmplidh ann airson a dhearbhadh agus tha làimhseachadh le aon peilear penicillin a tha ag obair o chionn fhada ag obair gu math, tha sifilis a’ fàs na dhuilgheadas mòr a-rithist air feadh an t-saoghail. Tha seo gu sònraichte fìor am measg dhaoine aig a bheil gnè ri fir (MSM) ann an dùthchannan le teachd a-steach àrd is meadhanach. Fhad ‘s a tha cuid de dhùthchannan le teachd-a-steach ìosal air amasan WHO a choileanadh gus stad a chuir air syphilis a’ dol bho mhàthair gu pàisde, tha àrdachadh draghail ann an sifilis am measg MSM HIV-adhartach.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Grùthan Meudaichte: Gu tric lorgar seo agus faodaidh e tachairt ri taobh dinneag leudaichte. Le bhith a’ sgrùdadh biopsy grùthan fo mhiocroscopaidh raon dorcha dh’ fhaodadh gu bheil an spirochete ann. Faodaidh deuchainnean gnìomh grùthan neo-àbhaisteach nochdadh. (2) Buidheachadh a’ Chraicinn (Gnè) : Co-dhiù a tha cuideigin a’ nochdadh a’ bhuidheach an urra ri dè a’ bhuaidh a tha air an grùthan. (3) Sròn runny: Gu tric aon de na ciad shoidhnichean, mar as trice taobh a-staigh a 'chiad seachdain an dèidh breith. (4) Nòtaichean Lymph Swollen: Tha sèid coitcheann de nòsan lùbach, mar as trice gun phian, cuideachd cumanta. (5) Rash Craicinn: Mar as trice bidh broth a’ nochdadh aon no dà sheachdain às deidh an t-sròn runny. Is dòcha gum faic thu spotan beaga dearg no pinc air a’ chùl, cnapan, sliasaid, agus buinn nan casan. Faodaidh an broth seo a dhol air adhart gu bhith a’ feannadh agus a’ rùsgadh.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosis agus Làimhseachadh
Faodar VDRL agus RPR a chleachdadh gus galar a dhearbhadh o chionn ghoirid agus sgrion airson sifilis. Tha deuchainn FTA-ABS na dheuchainn nas sònraichte agus faodar a chleachdadh gus sgrùdadh a dhèanamh airson eachdraidh ghalaran roimhe. Tha penicillin air a chleachdadh airson syphilis a làimhseachadh.