Syphilis - Sifilis
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Chancres – prìomh ghalair syphilitic a tha adhbharach le Treponema pallidum
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ReferencesIs e galar gnèitheach a th’ ann an sifilis a tha air adhbhrachadh le am bacterium Treponema pallidum. Anns an sgrùdadh seo, bidh sinn a’ cuimseachadh air euslaintich aig aois 18–68 le sifilis àrd‑ìre.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Tha sifilis na ghalar bhactair air adhbhrachadh le Treponema pallidum. Faodaidh i adhbharachadh atharrachaidhean air diofar ghalaran, a’ cosnadh a’ far-ainm “great imitator”. Tha sifilis fhathast a’ toirt buaidh air milleanan air feadh na cruinne, ach gabhaidh a làimhseachadh gu h‑èifeachdach le penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Bidh Treponema pallidum ag adhbhrachadh sifilis tro cheangal gnèitheasach no bho mhàthair gu pàisde fhad ’s a tha thu trom. Ged a tha deuchainnean sìmplidh ann airson a dhearbhadh agus tha làimhseachadh le aon peilear penicillin a tha ag obair gu math fad ùine, tha sifilis a’ fàs na dhuilgheadas mòr a‑rithist air feadh an t‑saoghail. Tha seo gu sònraichte fìor am measg dhaoine aig a bheil gnè ri fir (MSM) ann an dùthchannan le teachd‑a‑steach àrd is meadhanach. Fhad ’s a tha cuid de dhùthchannan le teachd‑a‑steach ìosal a’ coileanadh amasan WHO gus stad a chur air sifilis a’ dol bho mhàthair gu pàisde, tha àrdachadh draghail ann an sifilis am measg MSM HIV‑adhartach.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Grùthan Meudaichte: Gu tric, lorgar seo agus faodaidh e tachairt ri taobh dinneag leudaichte. Le bhith a’ sgrùdadh biopsi de na grùthan fo mhicrosgopaidh ann an raon dorcha, dh’ fhaodadh gun deach an spirochete a lorg. Faodaidh deuchainnean gnìomh grùthan neo-àbhaisteach nochdadh. (2) Buidheachadh a’ Chraicinn (Gnè): Co-dhiù, tha cuideigin a’ nochdadh buaidh a’ bhuidheach air an grùthan. (3) Sròn runny: Gu tric, tha seo am measg na ciad shoidhnichean, gu tric taobh a‑staigh a' chiad seachdain an dèidh breith. (4) Nòtaichean Lymph Swollen: Tha sèid coitcheann de nòsan lùbach, gu tric gun phian, ach cumanta. (5) Rash Craicinn: Mar as trice, bidh broth a’ nochdadh aon no dà sheachdain às deidh an t‑sròn runny. Is dòcha gun faic thu spotan beaga dearg no pinc air a’ chùl, cnapan, sliasaid, agus buinn nan casan. Faodaidh an broth seo a dhol air adhart gu bhith a’ feannadh agus a’ rùsgadh.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosadh agus Làimhseachadh
Faodar VDRL agus RPR a chleachdadh gus an t‑galar a dhearbhadh gu luath agus airson sgrìobhadh. Tha deuchainn FTA‑ABS na dheuchainn nas sònraichte agus faodar a chleachdadh gus eachdraidh ghalaran roimhe a sgrùdadh. Tha penicillin air a chleachdadh airson syphilis a làimhseachadh.