Acne
☆ Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas.
Acne na zona do torso. A parte superior do torso e as costas son áreas comúns de acne.
References
O acne, a condición da pel máis común nos Estados Unidos, é un problema inflamatorio persistente da pel. O tratamento ten como obxectivo abordar catro factores principais que contribúen ao acne: a produción excesiva de sebo, a acumulación de células da pel, a colonización de Propionibacterium acnes e a inflamación resultante. Os retinoides tópicos xestionan eficazmente as lesións inflamatorias e non inflamatorias ao previr e reducir os comedóns ao tempo que abordan a inflamación. O peróxido de benzoilo, dispoñible sen receita, é un axente bactericida sen promover a resistencia bacteriana. Aínda que os antibióticos tópicos e orais funcionan sós, combinalos con retinoides tópicos mellora a súa eficacia. Engadir peróxido de benzoilo á terapia con antibióticos reduce o risco de resistencia bacteriana. A isotretinoína oral, aprobada para o acne grave e teimudo, adminístrase a través do programa iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Os tratamentos tópicos comúns para o acne inclúen benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Os antibióticos orais foron durante moito tempo unha parte fundamental do tratamento do acne, especialmente para casos moderados a graves. Funcionan mellor cando se usan xunto cun retinoide tópico e BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin mostraron todos probas de eficacia.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Os retinoides tópicos sempre se recomendan para tratar o acne. Cando se usan antibióticos sistémicos ou tópicos, é importante combinalos con peróxido de benzoilo e retinoides, pero só durante 12 semanas. Isotretinoin está reservado para casos graves de acne que non responderon a outros tratamentos. Aínda que hai algunha evidencia de tratamentos físicos como terapia con láser e peelings químicos, así como enfoques complementarios como o veleno de abella purificado e certas dietas, a súa eficacia aínda é incerta.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Varios estudos analizaron como os diferentes alimentos afectan o acne nos pacientes. Descubriron que as persoas con acne que comen alimentos cunha carga glicémica baixa tenden a ter menos puntos de acne en comparación con aqueles que comen alimentos cunha carga glicémica alta. Tamén se estudou os produtos lácteos en relación ao acne. Parece que certas proteínas do leite poden contribuír máis ao acne que a graxa ou o contido global de lácteos. Outras investigacións centráronse nos ácidos graxos omega-3 e o ácido γ-linoleico. Suxire que as persoas con acne poden beneficiarse de comer máis peixe e aceites saudables para aumentar a inxestión destes ácidos graxos. Estudos recentes sobre probióticos para o acne mostran resultados prometedores, pero son necesarias máis investigacións para confirmar estes primeiros descubrimentos.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
En ambos os sexos, as hormonas chamadas andróxenos parecen formar parte do mecanismo subxacente, ao provocar un aumento da produción de sebo. Outro factor común é o crecemento excesivo da bacteria Cutibacterium acnes, que está presente na pel.
Os tratamentos aplicados directamente á pel afectada, como o ácido azelaico, o peróxido de benzoilo e o ácido salicílico, úsanse habitualmente. Os antibióticos e os retinoides están dispoñibles en formulacións que se aplican á pel e se toman por vía oral para o tratamento do acne. Non obstante, a resistencia aos antibióticos pode desenvolverse como resultado da terapia con antibióticos. Varios tipos de pílulas anticonceptivas poden axudar a previr o acne nas mulleres. O tratamento precoz e agresivo do acne mediante isotretinoína pode ser útil para diminuír a complicación a longo prazo dos individuos.
○ Tratamento
O xel de adapaleno pódese usar amplamente porque suprime a secreción de sebo e ten o efecto de suprimir a recorrencia do acne. O xel de adapaleno pode irritar a pel se se aplica demasiado inicialmente. O peróxido de benzoilo e o ácido azelaico, por outra banda, pódense usar en sitios de acne inflamatorio porque axudan coa inflamación. En xeral, é necesario un tratamento a longo prazo de 1 mes ou máis para ver un efecto.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction