Acne
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Acne na zona do torso. A parte superior do torso e as costas son áreas comúns de acné.
relevance score : -100.0%
ReferencesO acné, a condición da pel máis común nos Estados Unidos, é un problema inflamatorio persistente. O tratamento ten como obxectivo abordar catro factores principais que contribúen ao acné: a produción excesiva de sebo, a acumulación de células da pel, a colonización de Propionibacterium acnes e a inflamación resultante. Os retinoides tópicos xestionan eficazmente as lesións inflamatorias e non inflamatorias, ao previr e reducir os comedóns e ao mesmo tempo abordar a inflamación. O benzoyl peroxide, dispoñible sen receita, é un axente bactericida que non promove a resistencia bacteriana. Aínda que os antibióticos tópicos e orais funcionan sozinhos, combinalos con retinoides tópicos mellora a súa eficacia. Engadir benzoyl peroxide á terapia con antibióticos reduce o risco de resistencia bacteriana. O isotretinoin oral, aprobado para o acné grave e teimudo, adminístrase a través do programa iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Os tratamentos tópicos máis comúns para o acné inclúen benzoyl peroxide (BP), salicylic acid, antibiotics, combinacións de antibiotics con BP, retinoids, combinacións de retinoids con BP ou antibiotics, azelaic acid e agentes sulfonas. Os antibióticos orais foron, durante moito tempo, unha parte fundamental do tratamento do acné, especialmente nos casos moderados a graves. Funcionan mellor cando se usan xunto cun retinoide tópico e BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin e cephalexin mostraron probas de eficacia.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Os retinoides tópicos recoméndanse sempre para tratar o acné. Cando se usan antibióticos sistémicos ou tópicos, é importante combinalos con peróxido de benzoilo e retinoides, pero só durante 12 semanas. Isotretinoin está reservado para casos graves de acné que non responderon a outros tratamentos. Aínda que existen evidencias de tratamentos físicos, como a terapia con láser e os peelings químicos, así como enfoques complementarios, como o veneno de abella purificado e certas dietas, a súa eficacia segue sendo incerta.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Varios estudos analizaron como os diferentes alimentos afectan o acné nos pacientes. Descubriron que as persoas con acné que comen alimentos cunha carga glicémica baixa tiñen menos puntos de acné en comparación con aqueles que consumen alimentos cunha carga glicémica alta. Tamén se estudou a relación dos produtos lácteos co acné. Parece que certas proteínas do leite poden contribuír máis ao acné que a graxa ou o contido global dos lácteos. Outras investigacións centráronse nos ácidos graxos omega‑3 e no ácido γ‑linoleico. Suxiren que as persoas con acné poden beneficiarse de comer máis peixe e aceites saudables para aumentar a inxestión destes ácidos graxos. Estudos recentes sobre probióticos para o acné mostran resultados prometedores, pero son necesarias máis investigacións para confirmar estes primeiros descubrimentos.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
En ambos os sexos, as hormonas chamadas andróxenos parecen formar parte do mecanismo subxacente, ao provocar un aumento da produción de sebo. Outro factor común é o crecemento excesivo da bacteria Cutibacterium acnes, que está presente na pel.
Os tratamentos aplicados directamente á pel afectada, como o ácido azelaico, o peróxido de benzoilo e o ácido salicílico, úsanse habitualmente. Os antibióticos e os retinoides están dispoñibles en formulacións tópicas e orais para o tratamento do acne. Non obstante, a resistencia aos antibióticos pode desenvolverse como resultado da terapia antibiótica. Varios tipos de pílulas anticonceptivas poden axudar a previr o acne nas mulleres. O tratamento precoz e agresivo do acne mediante isotretinoína pode ser útil para reducir as complicacións a longo prazo.
○ Tratamento
O gel de adapaleno pódese usar amplamente porque suprime a secreción de sebo e reduce a recorrencia do acne. O gel de adapaleno pode irritar a pel se se aplica en exceso nas primeiras aplicacións. O peróxido de benzoilo e o ácido azelaico, por outra banda, pódense usar en áreas de acne inflamatorio porque axudan a controlar a inflamación. En xeral, é necesario un tratamento a longo prazo, de un mes ou máis, para observar un efecto.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction