Angiofibroma
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References
Cutaneous angiofibromas pode aparecer en varias partes do corpo. Na cara, a miúdo coñécense como pápulas fibrosas ou adenoma sebáceo; no pene, chámanse pearly penile papules ; debaixo da unha, chámanse angiofibromas periungueais ou tumores de Koenen; e na boca, chámanse fibromas orais. Os angiofibromas faciais son unha característica destacada de tuberous sclerosis (TS) , un trastorno hereditario que afecta a pel, os riles, o corazón, o cerebro e os pulmóns. Normalmente desenvólvense na cara durante a infancia ou a primeira idade adulta en individuos con TS. Ter tres ou máis angiofibromas faciais ou dous ou máis angiofibromas periungueais considérase significativo no diagnóstico de TS. Ademais, poden estar presentes múltiples angiofibromas faciais en condicións (multiple endocrine neoplasia type 1 (MEN-1) e Birt-Hogg-Dubé syndrome) . Pearly penile papules atópanse ao longo da marxe coronal e do surco do pene. Son protuberancias persistentes e indoloras que se ven con máis frecuencia nos homes non circuncidados.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) cara
Fibrous papule
2) pene
Pearly penile papule
3) debaixo dunha unha ou unha do pé
Periungual angiofibroma