Drug eruption
☆ Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas.
Drug eruption caracterízase por afectar a todo o corpo.
References
As reaccións cutáneas causadas por medicamentos, coñecidas como erupcións de drogas, ás veces poden ser graves. Estas reaccións graves, chamadas severe cutaneous adverse drug reactions (SCARs) , considéranse potencialmente mortales. Inclúen condicións como Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Aínda que os SCARs son raros, ao redor do 2% dos pacientes hospitalizados os experimentan.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Unha muller de 31 anos visitou o departamento de dermatoloxía cunha mancha vermella indolora na parte superior do pé dereito. Ela tomou unha dose de doxiciclina (100 mg) o día anterior, despois do tratamento con láser de picosegundo para as cicatrices do acne. O ano pasado, ela experimentou un problema similar no mesmo lugar despois de tomar a mesma dose de tratamento con doxiciclina post-láser. Non ten antecedentes médicos significativos nin outros síntomas, como febre, local ou en todo o seu corpo.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) e toxic epidermal necrolysis (TEN) son dúas formas de reacción cutánea grave, diferentes doutras afeccións cutáneas como o eritema multiforme maior e a síndrome da pel escaldada por estafilococos, así como as reaccións aos medicamentos. SJS/TEN é unha reacción rara e grave que causa danos xeneralizados na pel e nas mucosas, a miúdo con síntomas sistémicos. En máis do 80% dos casos, os medicamentos son a causa.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
As erupcións de drogas son diagnosticadas principalmente a partir da historia clínica e do exame clínico. Tamén poden ser útiles unha biopsia cutánea, análises de sangue ou probas inmunolóxicas.
Exemplos de fármacos comúns que causan a erupción son os antibióticos e outras drogas antimicrobianas, as sulfamidas, os antiinflamatorios non esteroides (AINE), os axentes de quimioterapia para as neoplasias malignas, os anticonvulsivos e os psicotrópicos.
○ Diagnóstico e Tratamento
Se tes febre (aumento da temperatura corporal), debes buscar atención médica o antes posible. O fármaco sospeitoso debe ser interrompido (por exemplo, antibióticos, antiinflamatorios non esteroides). Antes de visitar o hospital, os antihistamínicos orais como cetirizina ou loratadina poden axudar a coceira e erupción cutánea.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Análise de sangue (CBC, LFT, reconto de eosinófilos)
Esteroides orais e antihistamínicos con receita médica