Melasma
https://en.wikipedia.org/wiki/Melasma
☆ Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas. 

É unha condición común observada en mulleres asiáticas de 40 anos. A lesión rodeada na foto está máis preto do lentigo que do melasma.
relevance score : -100.0%
References
Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 NIH
Recentemente, o láser low-fluence Q-switched Nd:YAG (LFQSNY) fíxose popular para tratar o melasma, especialmente en Asia. Resumir diversos estudos foi un reto, pero LFQSNY parece xeralmente efectivo e seguro para o melasma en comparación coas terapias tradicionais. Non obstante, algúns casos de hipopigmentación moteada foron informados como un efecto secundario de LFQSNY, posiblemente debido á alta enerxía do láser. O uso agresivo de LFQSNY tamén pode provocar hiperpigmentación pola inflamación, especialmente nos tons de pel máis escuros.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentation Disorders: Diagnosis and Management 29431372Os problemas de pigmentación adoitan atoparse na atención primaria. Os tipos comúns de trastornos da hiperpigmentación inclúen post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
O melasma non se pode resolver con tratamento con láser durante un período de tempo determinado, xa que é unha enfermidade na que se produce pigmento continuamente. O ácido tranxenémico axuda a mellorar para reducir a pigmentación.
○ Tratamento
Nalgúns países (por exemplo, Xapón, Corea), o ácido tranexámico oral está dispoñible sen receita e é eficaz. A crema de melasma con ácido tranexámico e ácido azelaico pode ser parcialmente útil.
A hidroquinona pódese usar tópicamente para o tratamento da hiperpigmentación, pero a FDA detivo os produtos OTC que conteñen hidroquinona a partir de 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma