Dysplastic nevus
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Dysplastic nevi ― Ana ba da shawarar biopsy ga mutanen Yamma.
References
Dysplastic nevus , wanda kuma aka sani da atypical ko Clarks nevus, ya haifar da muhawara a cikin ilimin cututtukan fata da cututtukan fata. Likitoci sukan bibiyar waɗannan moles ɗin saboda suna iya kama da rashin daidaituwa kuma suna haifar da damuwa game da melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , wanda kuma aka sani da atypical ko Clark nevi, wani lokacin na iya haifar da melanoma. Kusan kashi 36% na melanoma ana samun su kusa da dysplastic nevi. Alamomin cewa dysplastic nevus na iya juyewa zuwa melanoma sun haɗa da siffa marar daidaituwa, ƙarin canjin launi, ko launin toka. Wadannan ciwon daji yawanci suna faruwa a lokacin ƙuruciya (kusan tsakiyar shekaru talatin) , na iya zama da yawa, kuma galibi suna kan gangar jikin. A zahiri, dysplastic nevi suna tsakanin benign nevi da melanoma. Amma, kawai kashi 20 zuwa 30% na melanoma sun fito ne daga nevi da ke akwai.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma wani nau'i ne na ƙari wanda ke samuwa lokacin da melanocytes, kwayoyin da ke da alhakin launin fata, sun zama masu ciwon daji. Melanocytes sun samo asali ne daga jijiyoyi. Wannan yana nufin cewa melanoma na iya haɓaka ba kawai akan fata ba har ma a wasu wuraren da ƙwayoyin jijiyoyi ke ƙaura, kamar ƙwayar gastrointestinal da kwakwalwa. Adadin rayuwa ga marasa lafiya tare da melanoma na farko (mataki na 0) yana da girma a 97%, yayin da ya ragu sosai zuwa kusan 10% ga waɗanda aka gano suna da ciwon mataki na gaba (mataki IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Cancer risk
Kamar yadda aka gani a cikin mutanen Caucasian a Amurka, waɗanda ke da dysplastic nevi suna da haɗarin rayuwa na haɓaka melanoma fiye da 10%. A gefe guda, waɗanda ba tare da kowane dysplastic nevus suna da haɗarin haɓaka melanoma na ƙasa da 1%.
○ Tsaka ga mutanen da ke da dysplastic nevi
Ana ba da shawarar yin gwajin kai da fata don hana melanoma (ta hanyar gano nevi mai lalacewa wanda za a iya cirewa) ko don gano ciwace-ciwacen da ke akwai. Mutanen da ke da tarihin kansa ko tarihin iyali na ciwon daji na fata ko na nevi da yawa ya kamata su ga likitan fata aƙalla sau ɗaya a shekara don tabbatar da cewa ba sa haɓakar melanoma.
Gajartawar [ABCDE] ta kasance da amfani don taimakawa masu ba da lafiya da masu zaman kansu su tuna da mahimman halayen melanoma. Abin takaici ga matsakaicin mutum, yawancin keratoses na seborrheic, wasu lentigo senilis, har ma da warts na iya samun halayen [ABCDE], kuma ba za a iya bambanta da melanoma ba.
○ [ABCDE]
Asymmetrical: Asymmetrical fata rauni.
Border: Iyakar cutar ba bisa ka'ida ba.
Color: melanoma yawanci suna da launuka marasa daidaituwa.
Diameter: nevi fiye da 6 mm sun fi zama melanoma fiye da ƙananan nevi.
Evolution: Juyin halitta (watau canji) na nevus ko rauni na iya nuna cewa raunin yana zama m.