Erythema multiforme
☆ A cikin sakamakon Stiftung Warentest na 2022 daga Jamus, gamsuwar mabukaci tare da ModelDerm ya ɗan yi ƙasa kaɗan fiye da biyan shawarwarin telemedicine.
Erythema multiforme minor ― Lura cewa cibiyoyin raunukan na iya bushewa.
Urticaria kuma ana iya la'akari da shi azaman ganewar asali.
References
Erythema multiforme (EM) yanayi ne da ke fitowa fili irin tabo mai kama da fata da kuma mucosa saboda halayen rigakafi. Ko da yake sau da yawa yana haifar da cututtuka na hoto, musamman cutar ta herpes simplex (HSV) , ko wasu magunguna, har yanzu ba a san dalilin ba a yawancin lokuta. Yin maganin EM mai tsanani yana mai da hankali kan sauƙaƙa alamun alamun ta amfani da creams masu ɗauke da steroids ko antihistamines. Gudanar da maimaitawar EM yana da tasiri idan aka keɓance shi ga kowane majiyyaci. Hanyoyi na farko sun ƙunshi duka jiyya na baka da na waje. Waɗannan sun haɗa da corticosteroids da magungunan antiviral. Jiyya na Topical sun ƙunshi maƙarƙashiya masu ƙarfi na steroids da mafita ga maƙarƙashiya da abin ya shafa. Ga marasa lafiya da ba su da maganin rigakafi, zaɓuɓɓukan layi na biyu sun haɗa da magunguna masu hana rigakafi, maganin rigakafi, anthelmintics, da magungunan zazzabin cizon sauro.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
A yawancin lokuta, m erythema multiforme yana tafiya da kansa a cikin makonni 2 zuwa 4. Stevens-Johnson ciwo, wani mummunan yanayi da ya shafi mucous membranes, zai iya wuce har zuwa 6 makonni. Ba a ba da shawarar steroids don lokuta masu laushi ba. Ko ya kamata a yi amfani da steroids don tsananin erythema multiforme ba shi da tabbas tun da babu wani tabbataccen bincike daga binciken da bazuwar da ke nuna wanda yara za su amfana daga wannan magani.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Mun gabatar da wani nau'i na erythema multiforme (EM) na baka wanda TMP/SMX ke haifar da shi, yana nuna alamun cututtukan baki da na lebe ba tare da raunin fata ba. Wannan yana nuna bukatar banbance shi da sauran cututtukan cututtukan baki. Mai haƙuri ya sami maganin bayyanar cututtuka da allunan prednisolone, wanda ke haifar da haɓakawa bayan dakatar da maganin TMP / SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme shine yanayin da ya shafi fata da kuma wani lokacin mucosa, wanda tsarin rigakafi ke haifar da shi. Yawanci, yana bayyana azaman raunuka-kamar manufa, waɗanda zasu iya bayyana a ware, maimaituwa, ko nacewa. Waɗannan raunuka yawanci suna shafar ƙarshen ƙarshen, musamman saman su na waje. Babban abubuwan da ke haifar da cututtuka sun haɗa da cututtuka irin su herpes simplex virus da Mycoplasma pneumoniae, da kuma wasu magunguna, rigakafi, da cututtuka na autoimmune. Rarraba erythema multiforme daga urticaria ya dogara da tsawon lokacin raunuka; erythema multiforme raunuka sun kasance a kayyade aƙalla kwanaki bakwai, yayin da raunukan urticarial sukan ɓace a cikin yini ɗaya. Ko da yake kama, yana da mahimmanci don bambance erythema multiforme daga mafi tsananin ciwo na Stevens-Johnson, wanda yawanci ke gabatar da erythematous erythematous ko purpuric macules tare da blisters. Sarrafa erythema multiforme ya haɗa da taimako na alama tare da steroids na sama ko maganin antihistamines da magance tushen dalilin. Don lokuta masu zuwa da ke hade da cutar ta herpes simplex, ana ba da shawarar maganin rigakafi na rigakafi. Tsananin shigar mucosal mai tsanani na iya buƙatar asibiti don magudanar jini da maye gurbin electrolyte.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Yanayin ya bambanta daga ƙananan kurji mai ƙarancin kai zuwa wani nau'i mai haɗari, mai haɗari da rayuwa wanda aka sani da erythema multiforme babba wanda kuma ya haɗa da mucous membranes. Mamayewar jikin mucosa ko kasancewar bulaes sune mahimman alamun tsanani.
- Erythema multiforme minor: na al'ada hari ko tashe, edematous papules rarraba acrally
Siffa mai laushi yawanci yana gabatar da ƙaiƙayi kaɗan (amma ƙaiƙayi na iya zama mai tsanani), ɗigon ruwan hoda-jajaye, daidaitacce kuma yana farawa a kan iyakar. Resolution na kurji a cikin kwanaki 7-10 shine al'ada a cikin wannan nau'i na cutar.
- Erythema multiforme major: na al'ada hari ko tashe, edematous papules rarraba acrally tare da hannu daya ko fiye da mucous membranes. Ragewar Epidermal ya ƙunshi ƙasa da kashi 10% na faɗin sararin jiki.
○ maganin - Magungunan OTC
Idan yana tare da zazzabi (hawan zafin jiki), ana ba da shawarar ziyarci asibiti da wuri-wuri.
Ya kamata a daina magungunan da ake zargi. (misali maganin rigakafi, magungunan anti-inflammatory marasa steroidal)
Magungunan antihistamines na baka irin su cetirizine da loratadine don itching.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]