Herpes zosterhttps://en.wikipedia.org/wiki/Shingles
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References Herpes Zoster and Postherpetic Neuralgia: Prevention and Management 29431387Shingles, wanda ya haifar da sake kunna cutar varicella zoster da ke da alhakin kaji, yana shafar kusan mutane miliyan 1 kowace shekara a Amurka, tare da haɗarin rayuwa na 30%. Wadanda ke da raunin tsarin garkuwar jiki sun fi saurin kamuwa da shingles, tare da alamun bayyanar cututtuka yawanci suna farawa da rashin lafiya, ciwon kai, da zazzabi mai sauƙi, tare da jin daɗin fata da ba a saba gani ba kwanaki kaɗan kafin bayyanar kurji. Wannan kurji, yawanci yana bayyana a wani yanki na musamman na jiki, yana ci gaba daga bayyanannun blisters zuwa ƙumburi a cikin mako guda zuwa kwanaki goma. Magani cikin gaggawa tare da magungunan rigakafin ƙwayar cuta (acyclovir, valacyclovir, or famciclovir) a cikin sa'o'i 72 na fara kurji yana da mahimmanci. Postherpetic neuralgia, rikice-rikice na yau da kullun da ke da alaƙa da tsayin daka a cikin yankin da abin ya shafa, yana shafar kusan ɗaya cikin marasa lafiya biyar kuma yana buƙatar ci gaba da gudanarwa tare da magunguna irin su gabapentin, pregabalin, ko wasu antidepressants, tare da wakilai na zahiri kamar lidocaine ko capsaicin. Ana ba da shawarar yin rigakafin cutar varicella zoster ga manya masu shekaru 50 zuwa sama don rage haɗarin shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Epidemiology, treatment and prevention of herpes zoster: A comprehensive review 29516900Herpes zoster yana faruwa akai-akai a cikin mutane masu shekaru 50 zuwa sama, waɗanda ke da raunin tsarin rigakafi, da masu shan magungunan rigakafi. Yana haifar da sake kunna cutar varicella-zoster, kwayar cutar da ke haifar da kaji. Alamun kamar zazzaɓi, zafi, da ƙaiƙayi yawanci suna gaban bayyanar kurjin. Mafi yawan rikice-rikice shine neuralgia na post-herpetic, wanda shine ciwon jijiyoyi na yau da kullum bayan kurjin ya share. Abubuwan haɗari da rikice-rikice masu alaƙa da zoster herpes sun bambanta dangane da shekaru, lafiyar rigakafi, da lokacin fara jiyya. An nuna allurar rigakafin ga mutane masu shekaru 60 zuwa sama don rage yawan abin da ya faru na herpes zoster da post-herpetic neuralgia. Fara magungunan rigakafi da masu rage jin zafi a cikin sa'o'i 72 na farawar kurji zai iya rage tsanani da rikitarwa na herpes zoster da post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Prevention of Herpes Zoster: A Focus on the Effectiveness and Safety of Herpes Zoster Vaccines 36560671 NIH
Gwaje-gwajen asibiti kafin amincewa sun nuna cewa rigakafin zoster mai rai yana aiki kusan 50 zuwa 70%, yayin da maganin sake haɗawa ya fi kyau, kama daga 90 zuwa 97%. A cikin bincike na duniya, suna goyan bayan binciken gwaje-gwajen, wanda ke nuna cewa rigakafin rayuwa yana da tasiri kusan kashi 46%, yayin da mai sake haɗawa ya kusan kashi 85%.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Chickenpox, wanda kuma ake kira varicella, yana fitowa daga kamuwa da cutar ta farko, yawanci yana faruwa a lokacin ƙuruciya ko samartaka. Da zarar kashin kajin ya warke, kwayar cutar za ta iya zama ba ta aiki (kwanciyar hankali) a cikin sel jijiya na mutum tsawon shekaru ko shekaru, bayan haka tana iya sake kunnawa. Sakamakon herpes zoster lokacin da aka sake kunna kwayar cutar varicella. Sannan kwayar cutar tana tafiya tare da jijiyoyi zuwa ƙarshen jijiyoyi a cikin fata, suna haifar da blisters. Yayin barkewar herpes zoster , kamuwa da kwayar cutar varicella da aka samu a cikin blisters na herpes zoster na iya haifar da kashin kaji a cikin wanda bai riga ya kamu da cutar ba.
Abubuwan da ke da haɗari don sake kunna kwayar cutar sun haɗa da tsufa, rashin aikin rigakafi, da kamuwa da cutar kaji kafin watanni 18. Cutar varicella zoster ba iri ɗaya ce da cutar ta herpes simplex ba, kodayake duka biyun suna cikin iyali ɗaya na ƙwayoyin cuta.
Alurar rigakafin herpes zoster suna rage haɗarin herpes zoster da 50% zuwa 90%. Hakanan yana rage ƙimar neuralgia na postherpetic, kuma, idan herpes zoster ya faru, tsananin sa. Idan herpes zoster ya tasowa, magungunan antiviral kamar aciclovir na iya rage tsanani da tsawon lokacin cutar idan an fara a cikin sa'o'i 72 na bayyanar kurji.
○ Magani
Idan raunuka suna yaduwa da sauri, ga likitan ku da wuri-wuri don maganin rigakafi.
Dukansu magungunan antiviral da magungunan neuralgia ana buƙata. Ya kamata ku huta kuma ku daina shan barasa.
#Acyclovir
#Fancyclovir
#Valacyclovir
#Gabapentin
#Pregabalin