Keloid
☆ A cikin sakamakon Stiftung Warentest na 2022 daga Jamus, gamsuwar mabukaci tare da ModelDerm ya ɗan yi ƙasa kaɗan fiye da biyan shawarwarin telemedicine.
Keloid bayan tiyata a wuyan hannu wanda aka yi masa magani tare da allurar intralesional na triamcinolone. Yankin erythema da ya nutse a gefen hagu shine wurin da aka yi magani.
Keloid Linear. Lokacin da suka faru a gaban babba na gangar jikin, sukan bayyana a cikin siffa mai layi.
Keloid na baya
Keloids a kan tafin ƙafafu na iya zama rashin jin daɗi don tafiya. Ana yin allurar steroid na ciki sau da yawa.
Keloids yawanci ana lura da su akan manyan hannaye.
Alamar bayyanar da keloid ƙirji.
References
Keloid yana samuwa saboda sabon waraka bayan rauni na fata ko kumburi. Abubuwan Halittu da Muhalli suna ba da gudummawa ga ci gaban su, tare da ƙarin ƙima a cikin mutane masu duhu na Afirka, Asiya, da zuriyar Hispanic. Keloid yana faruwa a lokacin da fibroblasts suka zama masu yawan aiki, suna samar da ƙwayar collagen da yawa da abubuwan girma. Wannan yana haifar da samuwar manyan ƙwayoyin collagen mara kyau da aka sani da keloidal collagen, tare da karuwa a cikin fibroblasts. A asibiti, keloids suna bayyana a matsayin m, nodules na roba a wuraren da suka ji rauni a baya. Ba kamar tabo na al'ada ba, keloid ya wuce asalin wurin rauni na asali. Marasa lafiya na iya samun ciwo, ƙaiƙayi, ko kuna. Ana samun jiyya iri-iri, gami da allurar steroid, cryotherapy, tiyata, radiotherapy, da maganin laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Binciken na yanzu yana nuna cewa gel na silicone ko zane-zane tare da allurar corticosteroid shine mafi kyawun magani na farko don keloids. Ana iya la'akari da ƙarin jiyya kamar intralesional 5-fluorouracil (5-FU) , bleomycin, ko verapamil, kodayake tasirin su ya bambanta. Magungunan Laser, lokacin da aka haɗa su tare da allurar corticosteroid ko magungunan ƙwayoyin cuta a ƙarƙashin ɓoye, na iya haɓaka shigar da kwayoyi. Don keloid mai jujjuyawa, cirewar tiyata da ke biye da maganin radiation nan da nan ya nuna yana da tasiri. A ƙarshe, an tabbatar da yin amfani da zanen silicone da magungunan matsa lamba don rage yiwuwar sake dawowa keloid.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
A halin yanzu, babu wani nau'i-nau'i-daidai-duk magani wanda ke ba da garantin ƙarancin komawa ga keloids akai-akai. Koyaya, zaɓuɓɓukan haɓaka, kamar amfani da lasers tare da steroids ko haɗa 5-fluorouracil tare da steroids, suna tabbatar da alƙawarin. Bincike na gaba zai iya mayar da hankali kan yadda sabbin jiyya, irin su sarrafa kitse na autologous ko magungunan tushen sel, aiki don sarrafa keloids.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Scars wani bangare ne na gama gari na tsarin warkarwa bayan raunin fata. Da kyau, tabo ya zama lebur, sirara, kuma ya dace da launin fata. Abubuwa da yawa na iya haifar da rauni mara kyau, kamar kamuwa da cuta, raguwar kwararar jini, ischemia, da rauni. Tabo masu kauri, duhu fiye da fatar da ke kewaye, ko raguwa da yawa na iya haifar da mahimman batutuwa tare da aikin jiki da lafiyar tunani.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Ana ganin tabo na Keloid akai-akai a cikin mutanen Afirka, Asiya, ko na Hispanic. Mutanen da ke tsakanin shekaru 10 zuwa 30 suna da haɓakar haɓakar keloid fiye da tsofaffi.
Kodayake yawanci suna faruwa ne a wurin da aka samu rauni, keloid kuma na iya tasowa ba tare da bata lokaci ba. Suna iya faruwa a wurin da aka huda har ma da wani abu mai sauƙi kamar pimple ko karce. Suna iya faruwa a sakamakon mummunan kuraje ko tabon kaji, kamuwa da cuta a wurin rauni, maimaita rauni a wani yanki, matsanancin tashin hankali na fata yayin rufe rauni ko wani jikin waje a cikin rauni.
Keloid scars zai iya tasowa bayan tiyata. Sun fi yawa a wasu shafuka, kamar kirjin tsakiya (daga sternotomy), baya da kafadu (yawanci sakamakon kuraje), da lobes na kunne (daga huda kunne). Hakanan suna iya faruwa akan huda jiki. Mafi yawan wuraren da aka fi sani da su sune kunnuwa, hannaye, yankin pelvic, da kuma kan kashin kwala.
Jiyya da ake samu sune magungunan matsa lamba, siliki gel sheeting, intra-lesional triamcinolone acetonide, cryosurgery, radiation, Laser far, Interferon, 5-FU da tiyata excision.
○ Magani
Ciwon hawan jini zai iya inganta tare da 5 zuwa 10 intralesional steroid injections na wata 1.
#Triamcinolone intralesional injection
Ana iya gwada maganin Laser don erythema da ke da alaƙa da tabo, amma allurar triamcinilone kuma na iya inganta erythema ta hanyar daidaita tabo.
#Dye laser (e.g. V-beam)