Onychomysosis
https://en.wikipedia.org/wiki/Onychomycosis
☆ A cikin sakamakon Stiftung Warentest na 2022 daga Jamus, gamsuwar mabukaci tare da ModelDerm ya ɗan yi ƙasa kaɗan fiye da biyan shawarwarin telemedicine. 

Ƙafar mutum tare da ciwon ƙusa na fungal makonni goma zuwa hanyar maganin baka na terbinafine. Lura da ƙungiyar haɓakar ƙusa mai lafiya a bayan sauran ƙusoshin da suka kamu da cutar.


Halin kamuwa da cututtukan fungal akan babban yatsan hannu.
relevance score : -100.0%
References
Onychomycosis: Current trends in diagnosis and treatment 24364524Magungunan antifungal na tsarin su ne mafi tasiri magani. Meta-analyses yana nuna ƙimar maganin mycotic kamar haka: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Juyawar ƙusa a lokaci ɗaya yana ƙara haɓaka ƙimar magani. Maganin magani tare da ciclopirox ba shi da tasiri sosai; yana da ƙimar gazawar da ta wuce 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis 28722883 NIH
Onychomycosis cuta ce ta fungal da ke shafar kusoshi. Lokacin da dermatophytes ke haifar da shi, ana kiran shi tinea unguium. Onychomycosis ya haɗa da cututtuka da dermatophytes, yeasts, da mold ke haifarwa. Matsalar farce ba ta haifar da cutar fungal ba ana kiranta nail dystrophy. Ko da yake yana iya shafar farce da farcen ƙafafu, farcen yatsa ya fi yawa. Wannan labarin ya tattauna fannoni daban-daban na onychomycosis na ƙafar ƙafa, kamar tasirinsa, nau'ikan asibiti, matakai, ganewar asali, da magani. Duk da yake ba barazanar rai ba, onychomycosis na iya haifar da matsaloli masu tsanani kamar cellulitis, sepsis, kamuwa da kashi, lalacewar nama, da asarar ƙusa.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine 31424802 NIH
Terbinafine magani ne da ke yaki da cututtukan fungal ta hanyar toshe squalene epoxidase. Yana da tasiri a kan nau'ikan fungi na fata da yawa kuma an amince da shi don magance naman gwari na ƙusa idan an sha baki. Duk da yake mafi yawan sakamako masu illa kamar ciwon kai da al'amurran ciki suna da ƙananan kuma suna tafiya da kansu, canje-canje a cikin dandano (dysgeusia) na iya bambanta daga m zuwa mai tsanani, wani lokaci yana haifar da asarar nauyi. Canje-canjen dandano na dindindin ba safai ba ne amma an ba da rahoton.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis: An Updated Review 31738146 NIH
Onychomycosis cuta ce ta fungal da ke shafar kusoshi. Kusan kashi 90% na cututtukan farcen ƙafa da kashi 75% na ciwon farce suna haifar da fungi (Trichophyton mentagrophytes, Trichophyton rubrum) . Alamun sun hada da canza launin farce, kauri, rabuwa da gadon farce, da girma. Jiyya yawanci ya ƙunshi magunguna na baka kamar terbinafine ko itraconazole, tare da jiyya na cikin gida zaɓi ne don lokuta masu sauƙi zuwa matsakaici.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Maganin antifungal terbinafine da aka dauka da baki ya bayyana shine mafi inganci amma terbinafine yana hade da tasirin hanta.
Onychomysosis yana faruwa a kusan kashi 10 cikin ɗari na yawan mutanen da balagaggu, tare da manyan mutane da ke fama da cutar akai-akai. Maza suna fama da yawa fiye da mata. Onychomysosis yana wakiltar kusan rabin cutar ƙusa. Wannan yana nufin cewa nakasar farcen ƙafar ƙafar ƙafar ƙafar ƙafar ƙafar ƙafar ƙafar ƙafar ƙafa kuma na iya fitowa daga wasu abubuwan da ba na onychomycosis ba.
○ Jiyya - Magungunan OTC
Yana da wuya a yi maganin onychomycosis tare da magunguna na cikin gida saboda yana da wuya kwayoyi su shiga cikin kauri mai kauri.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Magani
Yawancin lokaci ana buƙatar magani na dogon lokaci har sai an cire farcen yatsa gaba ɗaya.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer