Panniculitishttps://en.wikipedia.org/wiki/Panniculitis
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References Erythema Nodosum: A Practical Approach and Diagnostic Algorithm 33683567 NIH
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis in Children 34449587 NIH
Panniculitis suna samar da rukuni mai ban sha'awa na cututtuka masu kumburi waɗanda suka haɗa da ƙwayar adipose na subcutaneous. Wadannan cututtuka ba su da yawa a cikin yara. Panniculitis na iya zama tsari na farko a cikin rashin lafiya na tsarin ko tsarin na biyu wanda ke haifar da kamuwa da cuta, rauni ko bayyanar da magani. Yawancin nau'in panniculitis suna da gabatarwa iri ɗaya na asibiti (ba tare da la'akari da aetiology ba) , tare da taushi, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Erythema nodosum - a review of an uncommon panniculitis 24746312Panniculitis , kumburin kitse na subcutaneous, yawanci yana gabatar da nodules masu kumburi. Erythema nodosum (EN) shine nau'in panniculitis mafi yawan lokuta a asibiti. Duk da yake har zuwa 55% na EN ana la'akari da idiopathic, abubuwan da suka fi dacewa sun haɗa da cututtuka, kwayoyi, cututtuka na tsarin kamar sarcoidosis da cututtukan hanji mai kumburi, ciki, da malignancy. EN yawanci yana gabatarwa a cikin matasa da 20s, kuma ana ganin su da yawa a cikin mata. Sau da yawa ana gabace shi da wani takamaiman tsari na makonni ɗaya zuwa uku, wanda zai iya haɗawa da zazzabi, rashin lafiya, da alamun kamuwa da ƙwayar cuta ta sama. Daga nan sai raunukan fata suka biyo baya, akasari ana yin su ne a bangaren extensor na gabobi. Raunukan suna da zafi zagaye ko m, an ɗaga su kaɗan, ja nodules marasa ciwon ciki. Ba a fahimci ainihin hanyar cutar ta EN ba, kodayake ana tsammanin sakamakon ya samo asali ne daga jibgewar hadaddun garkuwar jiki a cikin venules na septae a cikin kitse na ƙasa, yana haifar da panniculitis neutrophilic. Ko da ba tare da takamaiman magani don yanayin haɗari ba, EN yana warwarewa ba tare da magani ba a mafi yawan lokuta.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" wani nau'i ne na panniculitis wanda ke da jan nodules masu taushi, 1-10 cm, hade da alamun cututtuka ciki har da zazzabi, rashin lafiya, da ciwon haɗin gwiwa. Nodules na iya raguwa a cikin makonni 2-6 ba tare da kumburi ko tabo ba. Erythema nodosum yana hade da cututtuka, ciki har da Hepatitis C, EBV da tarin fuka, ciki, Non-Hodgkin lymphoma, da ciwon daji na pancreatic.