Karin bayani ― Hausa

Porokeratosis cuta ce ta fata da ba kasafai ake samu ba, wadda ke da matsalolin keratinization, kuma tana haifar da tashe, fasi mai siffar zobe ko kumburi mai ƙarfi a jikin fata. Ma'anar fasalinsa a ƙarƙashin na'urar hangen nesa ita ce kasancewar cornoid lamella, wani tsari na musamman na sel a saman fata. Porokeratosis na iya bayyana ta hanyoyi daban‑daban (disseminated superficial actinic porokeratosis, classical porokeratosis of Mibelli, porokeratosis palmaris plantaris et disseminatum, linear porokeratosis). Muhimmanci a lura cewa porokeratosis na iya haɓaka zuwa kansar fata. Hanya mafi inganci don tantance cutar porokeratosis ita ce biopsy a kan ɓangaren da aka samu canjin, ko da yake a halin yanzu babu ƙa'ida ta magani.
Porokeratosis is an uncommon dermatologic disorder. It is a disorder of keratinization that presents with keratotic papules or annular plaques with an elevated border. It has a distinct histologic hallmark of cornoid lamella, which is a column of tightly fitted parakeratotic cells in the upper epidermis. There are multiple clinical variants of porokeratosis, including disseminated superficial actinic porokeratosis, classical porokeratosis of Mibelli, porokeratosis palmaris plantaris et disseminatum, and linear porokeratosis. Porokeratosis is a precancerous lesion that can undergo malignant transformation. Evaluation of porokeratosis is best with a biopsy of the elevated border. There are no standard guidelines for treatment.

Disseminated superficial actinic porokeratosis (DSAP) cuta ce ta rashin keratinization. Yana ɗaya daga cikin nau'ikan porokeratosis guda shida, kuma yawanci yana shafar manyan yankuna idan aka kwatanta da sauran (linear, Mibelli's, punctate, palmoplantar disseminated, superficial porokeratosis). Nau'in porokeratosis mai fashewa yakan haɗu da ciwon daji, raunin garkuwar jiki, ko kumburi. Abubuwan haɗari sun haɗa da kwayoyin halitta, danne garkuwar jiki, da bayyanar rana. DSAP yana farawa da ƙwayoyin hoda ko launin ruwan kasa tare da tashe a gefuna a wuraren da rana ke fallasa, wani lokaci yana haifar da ƙaiƙayi kaɗan. Jiyya na iya bambanta kuma ya haɗa da kirim mai tsami, maganin haske, ko magunguna kamar 5-fluorouracil ko retinoids. Ana ɗaukar waɗannan raunuka a matsayin masu riga‑kafi, tare da 7.5‑10 % damar rikiɗa zuwa squamous cell carcinoma ko basal cell carcinoma.
Disseminated superficial actinic porokeratosis (DSAP) is a disease of disordered keratinization. Disseminated superficial actinic porokeratosis is one of six variants of porokeratosis. It has more extensive involvement than most other variants. These other variants include linear porokeratosis, porokeratosis of Mibelli, punctate porokeratosis, porokeratosis palmaris et plantaris disseminata, and disseminated superficial porokeratosis. The eruptive form of porokeratosis is associated with malignancy, immunosuppression, and a proinflammatory state. Risk factors for porokeratosis include genetics, immunosuppression, and ultraviolet light. The lesions in disseminated superficial actinic porokeratosis start as pink to brown papules and macules with a raised border in sun-exposed areas that can be asymptomatic or slightly pruritic. There are many options for the treatment of disseminated superficial actinic porokeratosis, including topical diclofenac, photodynamic therapy (PDT), 5-fluorouracil (5-FU), imiquimod, vitamin D analogs, retinoids, and lasers. These lesions are considered precancerous. There is a 7.5 to 10% risk of malignant transformation to squamous cell carcinoma or basal cell carcinoma.

Wani mutum mai shekaru 52, wanda a baya yake da lafiya, ya kawo lebur mai siffar zobe a ƙarshen yatsan ƙafarsa na huɗu, wanda ya kasance tsawon shekaru biyu ba tare da haifar da wata alama ba. A farkon, leburin ya kasance ƙanana, mai wuya, sannan ya girma a waje na tsawon lokaci. Duk da ƙoƙarin magani daban‑daban kamar cryotherapy, creams, antifungals, da maganin rigakafi, ba a samu ingantaccen sakamako ba. Binciken da aka yi a hankali tare da dermoscopy ya nuna busasshiyar, jan cibiya mai kauri. Ƙaramin yanki na fata da aka ɗauka daga gefen leburin ya nuna rashin ci gaban kwayoyin halitta a saman fata, wanda ke tabbatar da cutar porokeratosis of Mibelli.
A 52-year-old man with no past medical history presented with an asymptomatic annular atrophic patch on the distal portion of the fourth toe of 2 years’ duration. The lesion began as a small keratotic papule that gradually enlarged centrifugally. He had received multiple treatments including cryotherapy, topical corticosteroids, antifungals, and antibiotics without improvement. Dermoscopic examination revealed a scaly atrophic erythematous central area with a sharply demarcated peripheral hyperkeratotic structure. A skin biopsy of the edge of the lesion revealed a cornoid lamella with a column of parakeratotic cells extending from an invagination of the epidermis with absence of granular layer. The clinicopathologic correlation was consistent with porokeratosis of Mibelli.