Prurigo nodularishttps://en.wikipedia.org/wiki/Prurigo_nodularis
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References Prurigo Nodularis 29083653 NIH
Prurigo nodularis yanayin fata ne mai dorewa mai dadewa wanda ke tattare da dunƙule masu ƙarfi da nodules, yawanci ana samun su a sassan waje na hannu da ƙafafu. Waɗannan ƙullun na iya bambanta da launi daga nama-toned zuwa ruwan hoda kuma suna da ƙaiƙayi sosai. Suna iya shafar mutane na kowane zamani kuma galibi ana danganta su da wasu yanayin fata waɗanda ke haifar da itching na yau da kullun, kamar atopic dermatitis. Zaɓuɓɓukan jiyya sun haɗa da magunguna masu ƙarfi na maganin ƙaiƙayi, magungunan da ke shafar tsarin rigakafi, da magungunan da ke kaiwa tsarin juyayi. Sarrafa prurigo nodularis yawanci ya ƙunshi magani na dogon lokaci.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Treatment-resistant prurigo nodularis: challenges and solutions 30881076 NIH
Jiyya yawanci ya ƙunshi yin amfani da creams ko alluran steroids a yankin da abin ya shafa. A cikin lokuta masu tsanani ko taurin kai, ana iya buƙatar jiyya kamar maganin haske ko magunguna waɗanda ke danne tsarin rigakafi. Thalidomide da lenalidomide zaɓuɓɓuka ne don lokuta masu tsanani, amma suna iya samun mummunar illa. Sabbin jiyya (opioid receptor antagonists, neurokinin-1 receptor antagonists) suna nuna alƙawarin yin maganin prurigo nodularis tare da ƙarancin illa idan aka kwatanta da thalidomide ko lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic Prurigo Including Prurigo Nodularis: New Insights and Treatments 37717255 NIH
Chronic prurigo wata cuta ce ta fata da ke da tsayin lokaci mai tsawo (yana dadewa sama da makonni 6) , raunin fata da ke da alaka da karce, da tarihin tabo akai-akai. Ya ƙunshi neuroinflammation da fibrosis a cikin fata.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo Nodularis: Review and Emerging Treatments 34077168Prurigo nodularis matsalar fata ce da za ta daɗe tana da ƙaiƙayi. Ba mu san ainihin abin da ke haifar da shi ba, amma da alama cewa al'amuran rigakafi da jijiyoyi suna taka rawa a cikin sake zagayowar ƙaiƙayi. A yanzu, babu wasu jiyya da FDA ta Amurka ta amince da su musamman don prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ maganin - Magungunan OTC
Wanke wurin da aka samu da sabulu baya taimakawa ko kadan kuma yana iya kara muni. Maganin shafawa na OTC steroid na iya taimakawa wajen rage alamun, amma yawanci suna buƙatar a shafa su na makonni da yawa don ingantawa. Ci gaba da shan maganin antihistamines shima yana taimakawa wajen rage ƙaiƙayi.
#OTC steroid ointment
#OTC antihistamine
○ maganin
#Intralesional triamcinolone injection