Toxic epidermal necrosis
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Halayen asarar fata na Toxic epidermal necrosis
References
Stevens-Johnson Syndrome (SJS) da Toxic Epidermal Necrolysis (TEN) yanayi ne da ba kasafai ba inda fata ke fuskantar babban necrosis da zubarwa. Dangane da jiyya, cyclosporine yana da tasiri sosai ga SJS, yayin da haɗuwa da immunoglobulin na ciki (IVIg) da corticosteroids suna aiki mafi kyau ga lokuta na SJS da TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Toxic epidermal necrolysis (TEN) cuta ce mai muni da fata ta haifar da wasu magunguna da aikin garkuwar jiki, wanda ke haifar da raguwa mai yawa daga saman fatar fata (epidermis) , wanda ke shafar sama da kashi 30% na saman jiki. TEN yana da adadin mace-mace sama da 20%, sau da yawa saboda cututtuka da wahalar numfashi. Tsayawa maganin da ke haifar da amsawa, samar da kulawar tallafi, da yin amfani da ƙarin jiyya na iya inganta sakamakon. Nazarin kwanan nan ya nuna cewa kwayoyi kamar cyclosporine, tumor necrosis factor alpha inhibitors, da haɗuwa da globulin na rigakafi na ciki da kuma corticosteroids na iya taimakawa, dangane da gwaje-gwajen da aka bazu da kuma nazarin binciken da yawa.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.
Dalilin da ya fi dacewa shine wasu magunguna irin su lamotrigine, carbamazepine, allopurinol, sulfonamide maganin rigakafi, da nevirapine. Abubuwan haɗari sun haɗa da HIV da lupus erythematosus na tsarin. Jiyya yawanci yana faruwa a asibiti kamar a cikin sashin ƙonawa ko sashin kulawa mai zurfi.
○ maganin
Wannan cuta ce mai tsanani, don haka idan laɓɓanka ko bakinka sun kamu ko fatar jikinka ta yi kumbura, ga likitanka da wuri-wuri.
Ya kamata a daina magungunan da ake tuhuma. (misali maganin rigakafi, magungunan anti-inflammatory marasa steroidal)