Urticarial vasculitis
☆ A cikin sakamakon Stiftung Warentest na 2022 daga Jamus, gamsuwar mabukaci tare da ModelDerm ya ɗan yi ƙasa kaɗan fiye da biyan shawarwarin telemedicine.
References
Urticarial vasculitis wani yanayi ne da ba kasafai ake yi masa alama da ciwon amya na dadewa ko maimaituwa ba. Duk da yake alamun fatar sa na iya kama da na yau da kullun na amya, sun kasance na musamman saboda amya suna tsayawa aƙalla sa'o'i 24 kuma suna iya haifar da tabo mai duhu bayan faɗuwa. Ko da yake sau da yawa ba a san dalilin da ya sa ba, wani lokaci ana iya haifar da shi ta wasu magunguna, cututtuka, cututtuka na autoimmune, cututtuka na jini, ko ciwon daji. Wasu nazarin sun ma danganta shi da COVID-19 da mura H1N1. Hakanan yana iya shafar sauran sassan jiki kamar tsoka, koda, huhu, ciki, da idanu. Yayin da wani nau'in gwajin nama zai iya tabbatar da ganewar asali, ba koyaushe ya zama dole ba. Jiyya yawanci yana farawa da maganin rigakafi, dapsone, colchicine, ko hydroxychloroquine don lokuta masu sauƙi. Don ƙarin lokuta masu tsanani, ana iya buƙatar magungunan da ke hana tsarin rigakafi kamar methotrexate ko corticosteroids. Kwanan nan, hanyoyin ilimin halitta (rituximab, omalizumab, interleukin-1 inhibitors) sun nuna alƙawarin ga lokuta masu wahala.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Wani mutum mai shekaru 35 ya shigo da tarihin kwanaki 15 na jajayen jajaye, masu raɗaɗi a cinyoyinsu da ƙafafu biyu, tare da ciwon haɗin gwiwa. Ya sami ciwon yoyon fitsari tsawon mako guda kafin kurjin ya bayyana. Fatarsa ta nuna wasu taushi, masu siffar zobe, wani bangare na balaga, jajayen alluna a bangarorin biyu na cinyoyinsa da kafafu. An ba shi prednisolone na baka (40mg / rana) har tsawon mako guda tare da maganin antihistamine mara barci (fexofenadine) . A cikin mako guda, duk rashes sun ɓace gaba ɗaya. Babu sauran rashi a cikin watanni 6 masu zuwa na duba-kai na yau da kullun.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ maganin - Magungunan OTC
Idan kuna da zazzabi (ƙarin zafin jiki), muna ba da shawarar ku nemi kulawar likita da wuri-wuri.
Ya kamata a daina maganin da ake zargi. (misali maganin rigakafi, magungunan anti-inflammatory marasa steroidal)
Magungunan antihistamines na baka irin su cetirizine ko loratadine don itching.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Maganin shafawa na steroid na OTC na iya zama marasa tasiri don ƙarancin ƙarfi. Ana buƙatar a yi amfani da shi sama da mako guda don ganin an inganta.
#Hydrocortisone ointment