Amyloidosis - Amiloidoza
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U rezultatima Stiftung Warentest iz Njemačke za 2022., zadovoljstvo potrošača s ModelDermom bilo je samo malo niže nego s plaćenim konzultacijama o telemedicini.
U rezultatima Stiftung Warentest iz Njemačke za 2022., zadovoljstvo potrošača s ModelDermom bilo je samo malo niže nego s plaćenim konzultacijama o telemedicini.
Klasične crte lica Amiloidoza (Amyloidosis)
relevance score : -100.0%
ReferencesU našu ambulantu došla je 26‑godišnja žena koja se žali na osip na nogama koji svrbi već 10 godina. Unatoč korištenju steroidnih krema i kreme s tazarotenom, osip se nije poboljšao. Nije imala značajnu obiteljsku povijest. Kad smo je pregledali, uočili smo uzdignute, grube mrlje na prednjoj strani nogu, što je odgovaralo bolesti pod nazivom lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis je rijetko kožno stanje povezano s upornim svrbežom nepoznatog uzroka. Obično se manifestira kao nakupine uzdignutih, bezbojnih mrlja na vanjskoj površini kože. Najčešće se javlja kod osoba u dobi od 50 do 60 godina, a nažalost, za njega ne postoji lijek. Dostupni tretmani trenutno ne pokazuju zadovoljavajuće rezultate.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis je dugotrajni svrbež kože. Poznat je po skupinama zadebljalih izbočina koje se uglavnom nalaze na leđima, potkoljenicama, bedrima i rukama. Kada se pregleda pod mikroskopom, Lichen amyloidosis pokazuje nakupljanje amiloida u gornjem sloju kože, zajedno sa zadebljanjem i povećanjem vanjskog sloja kože. Iako točan uzrok Lichen amyloidosis još nije u potpunosti shvaćen, prethodne studije povezale su ga s čimbenicima poput trljanja ili trenja kože, smrti stanica, virusnih infekcija i drugih. Čini se da je Lichen amyloidosis povezan s nekoliko drugih kožnih stanja, poput atopic dermatitis, lichen planus i mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Dijagnostika i liječenje
#Electrophoresis of blood or urine
#Skin biopsy