Riehl melanosis - Riehl Melanozahttps://en.wikipedia.org/wiki/Riehl_melanosis
Riehl Melanoza (Riehl melanosis) je oblik kontaktnog dermatitisa koji započinje pruriti, eritemom i pigmentacijom koja se postupno širi; kada dosegne određeni opseg, postaje stacionaran. Uzrok bolesti može biti izlaganje suncu nakon korištenja određenih parfema ili krema.

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      References Riehl Melanosis 32491369 
      NIH
      Riehl melanosis često se poznaje kao pigmentirani kontaktni dermatitis. To je vrsta kožnog stanja uzrokovanog alergijama, najčešće izazvanog mirisima i drugim tvarima u kozmetičkim proizvodima. Iako je klasificiran kao oblik dermatitisa, Riehl melanosis uzrokuje pigmentacijske promjene na koži uz minimalne znakove iritacije. Češći je kod osoba tamnije kože. Nedavna istraživanja su ispitala učinkovitost mid‑fluence QSNY 1064‑nm laser tretmana za uklanjanje duboke pigmentacije povezane s Riehl melanosisom. Druga studija kombinirala je različite terapije, uključujući low‑fluence 1064‑nm Q‑switched Nd:YAG laser, kremu s hydroquinone (hidrokinon) i oralni tranexamic acid (traneksamična kiselina), što je dovelo do značajnog poboljšanja kod većine pacijenata.
      Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
       Research Advances in the Treatment of Riehl’s Melanosis 37168093 
      NIH
      Riehl's melanosis je vrsta kožnog stanja uzrokovanog kontaktom s određenim alergenima i izlaganjem sunčevoj svjetlosti. Dovodi do brze, progresivne sivo‑smeđe pigmentacije kože, što može značajno utjecati na psihičko i fizičko stanje pacijenta. Iako je točan uzrok Riehl's melanosis još uvijek nepoznat, postojeća istraživanja ukazuju na jaku vezu s izloženošću alergenima. Za liječenje su isprobani i tradicionalni lijekovi i laserska terapija, često uz upotrebu sredstava za izbjeljivanje nanesenih na kožu. Laserska terapija, posebice pomoću Q‑switched Nd:YAG lasera, pokazala je obećavajuće rezultate u liječenju Riehl's melanosis. Kombinacija različitih pristupa liječenju dovela je do pozitivnih rezultata.
      Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.