Vitiligo
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Vitiligo na prstima je teže liječiti nego na drugim područjima. Osim što je kozmetički ružan, vitiligo je normalan i nije zarazan. U dermatologiji je najučinkovitiji tretman fototerapija ili laserski tretman (excimer) 2-3 puta tjedno tijekom najmanje 1 godine. Ako ne možete često ići u bolnicu zbog financijskih razloga ili zbog posla, možete isprobati aparat za fototerapiju koji je odobren za kućnu upotrebu.
Vitiligo očnih kapaka
Vitiligo na ruci
relevance score : -100.0%
ReferencesVitiligo je čest kožni poremećaj koji uzrokuje mrlje bijele kože zbog gubitka melanocita. Najnovija istraživanja pokazuju da je autoimuna bolest. Iako se često smatra kozmetičkim problemom, može duboko utjecati na mentalno blagostanje i svakodnevni život. Godine 2015. stručnjaci su odvojili tip pod nazivom segmental vitiligo od ostalih.
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
Pacijenti s aktivnim vitiligom imaju nekoliko mogućnosti terapije, kao što su sistemski glukokortikoidi, fototerapija i sistemski imunosupresivi. Stabilni pacijenti s vitiligom mogu pronaći olakšanje lokalnim kortikosteroidima, lokalnim inhibitorima kalcineurina, fototerapijom i postupcima transplantacije. Nedavni napredak u razumijevanju temeljnih procesa vitiliga doveo je do razvoja ciljanih terapija. Trenutačno JAK inhibitori najviše obećavaju; nude dobru podnošljivost i funkcionalne ishode, unatoč riziku od aktivacije latentnih infekcija i sistemskih nuspojava koje su uobičajene kod drugih imunosupresivnih lijekova. Istraživanje koje je u tijeku ima za cilj identificirati ključne citokine uključene u razvoj vitiliga (IFN‑γ, CXCL10, CXCR3, HSP70i, IL‑15, IL‑17/23, TNF). Blokiranje ovih citokina pokazalo se obećavajućim u životinjskim modelima i kod nekih pacijenata. Osim toga, u tijeku su istraživanja protiv miRNA‑based therapeutics i adoptive Treg cell therapy.
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
Ne postoji poznati lijek za vitiligo. Za osobe svijetle puti najčešće se preporučuju kreme za sunčanje i šminka. Druge mogućnosti liječenja mogu uključivati steroidne kreme ili fototerapiju.
○ liječenje
#Phototherapy
#Excimer laser
#Tacrolimus ointment