Acute generalized exanthematous pustulosis
Acute generalized exanthematous pustulosis (AGEP) se yon reyaksyon po ki ra ki gen rapò ak administrasyon medikaman nan 90% nan ka yo. Acute generalized exanthematous pustulosis karakterize pa eripsyon po toudenkou ki parèt an mwayèn senk jou apre yo fin kòmanse yon medikaman. Eripsyon sa yo se pustul, sa vle di ti eripsyon wouj blan oswa wouj nan po a ki gen materyèl twoub oswa purulan (pus). Blesi po yo anjeneral rezoud nan 1-3 jou apre yo sispann pran medikaman an.
☆ Nan rezilta Stiftung Warentest 2022 ki soti nan Almay, satisfaksyon konsomatè yo ak ModelDerm te sèlman yon ti kras pi ba pase ak konsiltasyon telemedsin peye.
Blesi toupatou ak eritem ak pustul parèt toudenkou.
References
Acute generalized exanthematous pustulosis (AGEP) se yon reyaksyon po ki make pa ti boul ki plen pi sou yon baz po wouj. Sa rive anjeneral lè yon moun pran sèten medikaman, tankou antibyotik, epi li gaye byen vit atravè kò a. Apre yo fin sispann medikaman an deklanche, sentòm yo anjeneral disparèt nan de semèn, souvan kite kèk koule po. Menmsi anjeneral pa grav epi limite a sa sèlman po a, ka grav yo ka klase ansanm ak lòt reyaksyon po grav tankou Stevens-Johnson syndrome oswa toxic epidermal necrolysis. Tretman se sitou swen sipò, ak pronostik pou rezolisyon konplè maladi a anjeneral ekselan.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Recent experimental data reviewed herein are supportive of an early role of drug-induced innate immune activation and innate cytokines such as interleukin (IL)-1, IL-36, and IL-17 in the pathogenesis of AGEP. This explains the rapid onset and neutrophilic character of the cutaneous inflammation.
Yon nonm 76-zan te vin nan sal ijans la paske po l 'te chanje nan de jou ki sot pase yo. Doktè yo te jwenn plak wouj ak zòn ki soulve sou kòf li, bra ak janm li. Kòm tan te pase, plak sa yo mete tèt yo ansanm, epi li te devlope boul ki tankou boul nan zòn wouj yo. Tès yo te montre gwo kantite globil blan ak anpil nan yon kalite yo rele netrofil, ak ogmante nivo C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
