Keloid
☆ Nan rezilta Stiftung Warentest 2022 ki soti nan Almay, satisfaksyon konsomatè yo ak ModelDerm te sèlman yon ti kras pi ba pase ak konsiltasyon telemedsin peye.
Yon keloid apre operasyon sou ponyèt la ki te trete ak piki entralesional triamcinolone. Zòn nan eritem koule sou bò gòch la se zòn nan trete.
Keloid lineyè. Lè yo rive sou devan anwo nan tors la, yo souvan parèt nan yon fòm lineyè.
Posyèr auricular Keloid
Keloid sou plant yo nan pye yo ka alèz pou mache sou. Piki esteroyid entralesional yo anjeneral fèt plizyè fwa.
Keloid yo souvan obsève sou bra yo anwo.
Manifestasyon tipik nan keloid nan pwatrin.
References
Keloid fòme akòz gerizon etranj apre blesi po oswa enflamasyon. Faktè jenetik ak anviwònman an kontribye nan devlopman yo, ak pi gwo pousantaj nan moun ki gen po nwa ki gen desandan Afriken, Azyatik ak Panyòl. Keloid rive lè fibroblast yo vin twò aktif, pwodui twòp kolagen an ak faktè kwasans. Sa a mennen nan fòmasyon nan gwo, pa nòmal kolagen an pakèt ke yo rele kolagen keloidal, ansanm ak yon ogmantasyon nan fibroblasts. Klinikman, keloids parèt tankou fèm, nodules kawoutchou nan zòn ki te blese précédemment. Kontrèman ak mak nòmal yo, keloids pwolonje pi lwen pase sit chòk orijinal la. Pasyan yo ka santi doulè, gratèl, oswa boule. Gen plizyè tretman ki disponib, tankou piki esteroyid, kriyoterapi, operasyon, radyoterapi, ak terapi lazè.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Rechèch aktyèl la sijere ke jèl silikon oswa fèy ansanm ak piki kortikoterapi se premye tretman pi pito pou keloid. Lòt tretman tankou entralesional 5-fluorouracil (5-FU) , bleomicin, oswa verapamil ka konsidere tou, byenke efikasite yo varye. Terapi lazè, lè konbine avèk piki kortikoterapi oswa estewoyid aktualite anba okluzyon, ka amelyore pénétration nan dwòg. Pou keloid rekalsitran, retire chirijikal ki te swiv pa terapi radyasyon imedya te montre efikas. Finalman, lè l sèvi avèk silikon fèy ak terapi presyon yo te pwouve diminye chans pou repetition keloid.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Kounye a, pa gen yon sèl-gwosè-adapte-tout tretman ki garanti yon to toujou ba repetisyon pou keloid. Sepandan, opsyon k ap grandi yo, tankou lè l sèvi avèk lazè ansanm ak estewoyid oswa konbine 5-fluorouracil ak estewoyid, yo pwouve pwomèt. Rechèch nan lavni ta ka konsantre sou kouman nouvo tretman, tankou grèf otològ grès oswa terapi ki baze sou selil souch, travay pou jere keloid.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Mak yo se yon pati komen nan pwosesis gerizon an apre blesi po. Idealman, mak yo ta dwe plat, mens, ak matche ak koulè po a. Anpil faktè ka mennen nan gerizon pòv blesi, tankou enfeksyon, sikilasyon san redwi, iskemi, ak chòk. Sikatris ki epè, ki pi fonse pase po ki antoure a, oswa ki retresi twòp ka lakòz pwoblèm enpòtan ak fonksyon fizik ak sante emosyonèl.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Sikatris keloid yo wè pi souvan nan moun ki gen desandan Afriken, Azyatik oswa Panyòl. Moun ki gen laj ant 10 ak 30 ane gen yon pi gwo tandans pou devlope yon keloid pase granmoun aje.
Malgre ke yo anjeneral rive nan sit la nan yon aksidan, keloid ka leve tou espontaneman. Yo ka rive nan sit la nan yon piercing e menm soti nan yon bagay ki senp tankou yon bouton oswa grafouyen. Yo ka rive kòm yon rezilta akne grav oswa sikatris varisèl, enfeksyon nan yon sit blesi, chòk repete nan yon zòn, twòp tansyon po pandan fèmen blesi oswa yon kò etranje nan yon blesi.
Mak keloid ka devlope apre operasyon. Yo pi komen nan kèk sit, tankou pwatrin santral la (ki soti nan yon sternotomi), do a ak zepòl (anjeneral ki soti nan akne), ak lòb zòrèy yo (soti nan piercing zòrèy). Yo ka rive tou sou piercing kò. Tach ki pi komen yo se lob zòrèy, bra, rejyon basen, ak sou zo kolye a.
Tretman ki disponib yo se terapi presyon, fèy jèl silicone, acetonide triamcinolòn entra-lesional, kriochiriji, radyasyon, terapi lazè, entèferon, 5-FU ak eksizyon chirijikal.
○ Tretman
Mak ipètrofik yo ka amelyore ak 5 a 10 piki esteroyid entralesional 1 mwa entèval.
#Triamcinolone intralesional injection
Tretman lazè ka eseye pou eritem ki asosye ak sikatris, men piki triamcinilone kapab tou amelyore eritem nan plati mak la.
#Dye laser (e.g. V-beam)