Plis enfomasyon ― Kreyòl ayisyen

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis fòme yon gwoup eterojèn maladi enflamatwa ki enplike tisi adipoz lar la. Maladi sa yo ra nan timoun yo. Pannikulit la kapab pwosesis prensipal nan yon maladi sistemik oswa yon pwosesis segondè ki soti nan enfeksyon, chòk oswa ekspoze a medikaman. Pifò kalite panikulit gen menm prezantasyon klinik la (kèlkeswa etyoloji a) , ak sansib, eritematoz lar nodil.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis, enflamasyon nan grès subkutan, anjeneral prezante ak nodul enflamatwa. Erythema nodosum (EN) se fòm panniculitis ki pi souvan nan klinik. Pandan ke jiska 55 % nan ka EN yo konsidere kòm idyopatik, kòz ki pi komen yo enkli enfeksyon, dwòg, maladi sistemik tankou sarkoidoz ak maladi entesten enflamatwa, gwosès, ak malignans. EN anjeneral parèt pandan adolesans ak nan ane 20 yo, epi li pi souvan obsève lakay fanm. Li souvan kòmanse ak yon prodwòm ki pa espesifik pandan youn a twa semèn, ki ka gen ladan lafyèv, malèz, ak sentòm enfeksyon aparèy respiratwa siperyè. Apre sa, blesi kutane yo parèt, tipikman sou aspè ekstansè manm yo. Blesi yo se nodil doulè ki awondi oswa oval, ki leve ti kras soti sou po a, ki pa ulseratif, epi ki wouj. Patojèn egzak EN pa konplètman konprann, byenke yo panse li se rezilta depo konplèks iminitè nan vèn ak septa grès subkutan, ki mennen a yon panniculitis netrofil. Menm san terapi espesifik pou kòz la, EN rezoud san tretman nan pifò ka yo.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.