Syphilis - Sifilis
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Chancres ― prensipal enfeksyon sifilitik pa Treponema pallidum
References
Sifilis se yon maladi transmisib seksyèlman koze pa bakteri Treponema pallidum. Nan etid sa a, nou konsantre sou 57 pasyan ki gen laj 18-68 ki gen sifilis segondè.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Sifilis se yon enfeksyon bakteri ki te koze pa Treponema pallidum. Li ka imite divès maladi, sa ki fè li tinon great imitator. Sifilis toujou afekte plizyè milyon atravè lemond, men yo ka trete yon fason efikas ak penisilin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum lakòz sifilis atravè kontak seksyèl oswa soti nan manman ak tibebe pandan gwosès la. Menmsi gen tès senp pou fè dyagnostik li ak tretman ak yon sèl piki penisilin ki dire lontan travay byen, sifilis ap vin tounen yon gwo pwoblèm ankò atravè lemond. Sa a se laverite espesyalman nan mitan gason ki fè sèks ak gason (MSM) nan peyi ki gen gwo ak mwayen revni. Pandan ke kèk peyi ki gen revni fèb yo te rankontre objektif OMS pou anpeche sifilis pase soti nan manman ak ti bebe, gen yon ogmantasyon mangonmen nan sifilis pami MSM ki gen VIH.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Fwa elaji: Sa a souvan jwenn epi li ka rive ansanm ak yon larat elaji. Egzamine yon byopsi fwa anba mikwoskopi fon nwa ka revele prezans spirochèt la. Tès fonksyon fwa yo ka montre anomali. (2) Po a jòn (Jònis) : Si yon moun montre lajònis depann de konbyen fwa a afekte. (3) Nen k ap koule: Souvan youn nan premye siy yo, anjeneral nan premye semèn apre nesans la. (4) Nœuds lenfatik anfle: anfle jeneralize nan gangliyon lenfatik, anjeneral, san doulè, se tou komen. (5) Gratèl sou po: Yon gratèl parèt anjeneral youn a de semèn apre nen k ap koule. Ou ka wè ti tach wouj oswa woz sou do a, bounda, kwis, ak plant pye yo. Gratèl sa a ka pwogrese nan dekale ak kwout.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Dyagnostik ak Tretman
VDRL ak RPR ka itilize pou konfime dènye enfeksyon ak tès depistaj sifilis. Tès FTA-ABS se yon tès ki pi espesifik epi yo ka itilize pou tcheke istwa enfeksyon anvan yo. Penicilin yo itilize pou trete sifilis.