Syphilis - Sifilishttps://en.wikipedia.org/wiki/Syphilis
Sifilis (Syphilis) se yon enfeksyon seksyèlman transmisib ki koze pa Treponema pallidum. Siy ak sentòm sifilis yo varye selon ki etap li prezante (primè, segondè, latent, ak siperyè). Etap primè a karakterize pa yon sèl chancre (yon ilsè po fèm, san doulè, ki pa grate, anjeneral ant 1 cm ak 2 cm an dyamèt), menm si ka gen plizyè chancre. Nan sifilis segondè, yon gratèl difize parèt, ki souvan enplike palmis men yo ak plant pye yo. Ka gen tou maleng nan bouch oswa nan vajen. Nan sifilis latent, ki ka dire plizyè ane, gen kèk sentòm oswa pa gen okenn sentòm. Nan sifilis siperyè, ka parèt gomme (mou, kwasans ki pa kansè), pwoblèm neurologik, oswa sentòm kadyak. Sifilis ka lakòz sentòm ki sanble ak anpil lòt maladi.

Dyagnostik ak Tretman
VDRL ak RPR ka itilize pou konfime enfeksyon an epi kòm tès depistaj sifilis. Tès FTA‑ABS se yon tès ki pi espesifik epi li ka itilize pou verifye istwa enfeksyon an. Penicillin itilize pou trete sifilis.

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  • Chancres — prensipal enfeksyon sifilitik ki koze pa Treponema pallidum
  • Jarisch-Herxheimer reaction ― Sifilis ak viris iminite defisyans imen
  • Syphilis segondè
References Secondary syphilis in cali, Colombia: new concepts in disease pathogenesis 20502522 
NIH
Sifilis se yon maladi transmisib seksyèl ki koze pa bakteri Treponema pallidum. Nan etid sa a, nou konsantre sou 57 pasyan ki gen laj ant 18 ak 68 ane ki gen sifilis segondè.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
 Syphilis 30521201 
NIH
Sifilis se yon enfeksyon bakteri ki koze pa Treponema pallidum. Li ka imite plizyè maladi, sa ki fè li “great imitator”. Sifilis afekte plizyè milyon moun atravè lemond, men li ka trete avèk efikasite lè w itilize penisilin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
 Syphilis 29022569 
NIH
Treponema pallidum lakòz sifilis atravè kontak seksyèl oswa soti nan manman ak ti bebe pandan gwosès la. Menm si gen tès senp pou fè dyagnostik li ak tretman ak yon sèl piki penisilin ki dire lontan ki travay byen, sifilis ap vin tounen yon gwo pwoblèm ankò atravè lemond. Sa a se laverite espesyalman nan mitan gason ki fè sèks ak gason (MSM) nan peyi ki gen gwo ak mwayen revni. Pandan ke kèk peyi ki gen revni fèb yo te reyalize objektif OMS pou anpeche sifilis pase soti nan manman ak ti bebe, gen yon ogmantasyon nan sifilis pami MSM ki gen VIH.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
 Congenital Syphilis 30725772 
NIH
(1) Fwa elaji: Sa a souvan jwenn epi li ka rive ansanm ak yon larat ki elaji. Egzamen yon byopsi fwa anba mikwoskòp fon nwa ka revele prezans spirochèt la. Tès fonksyon fwa yo ka montre anomali. (2) Po a jòn (Jònis): Lajònis la depann de kantite fwa ki afekte. (3) Nen k ap koule: Souvan youn nan premye siy yo, anjeneral nan premye semèn apre nesans la. (4) Nœuds lenfatik anfle: Anfle jeneralize nan gangliyon lenfatik, souvan san doulè, epi se tou komen. (5) Gratèl sou po: Yon gratèl parèt anjeneral youn a de semèn apre nen k ap koule. Ou ka wè ti tach wouj oswa woz sou do, bounda, kwis, ak plant pye yo. Gratèl sa a ka pwogrese, li ka dekale epi fòme kwout.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.