Toxic epidermal necrosis - Toksik Epidèrm Nekwozhttps://en.wikipedia.org/wiki/Toxic_epidermal_necrolysis
Toksik Epidèrm Nekwoz (Toxic epidermal necrosis) se yon kalite reyaksyon grav sou po. Sentòm bonè yo enkli lafyèv ak sentòm grip. Kèk jou apre po a kòmanse anpoul ak kale fòme zòn ki douloure ekaye. Li enpòtan ke manbràn mikez, tankou bouch la, yo tou tipikman enplike. Konplikasyon yo enkli dezidratasyon, sepsis, nemoni, ak echèk ògàn miltip.

Kòz ki pi komen se sèten medikaman tankou lamotrigin, carbamazepine, allopurinol, sulfonamide antibyotik, ak nevirapine. Faktè risk yo enkli VIH ak lupus sistemik eritematos. Tretman anjeneral pran plas nan lopital tankou nan yon inite boule oswa inite swen entansif.

○ Tretman
Sa a se yon maladi grav, kidonk si bouch ou oswa bouch ou afekte oswa po ou vin anpoul, wè doktè ou pi vit posib.
Dwòg ki sispèk yo ta dwe sispann. (egzanp antibyotik, dwòg anti-enflamatwa ki pa esteroyid)

☆ Nan rezilta Stiftung Warentest 2022 ki soti nan Almay, satisfaksyon konsomatè yo ak ModelDerm te sèlman yon ti kras pi ba pase ak konsiltasyon telemedsin peye.
  • Karakteristik pèt po nan Toksik Epidèrm Nekwoz (Toxic epidermal necrosis)
  • TENS ― jou 10
  • Necrolysis epidermalis toxica
  • Anpoul nan etap bonè yo ka byen vit pwogrese pou enplike tout kò a nan kèk jou.
References Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management 34577817 
NIH
Stevens-Johnson Syndrome (SJS) ak Toxic Epidermal Necrolysis (TEN) se kondisyon ki ra kote po a fè eksperyans gwo nekwoz ak koule. An tèm de tretman, cyclosporine trè efikas pou SJS, pandan y ap yon konbinezon de imunoglobulin venn (IVIg) ak kortikoterapi travay pi byen pou ka SJS ak TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
 Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches 36469487
Toxic epidermal necrolysis (TEN) se yon reyaksyon grav po ki te koze pa sèten medikaman ak aktivite sistèm iminitè, sa ki lakòz gwo echèl detachman nan kouch ekstèn po a (epiderm) , ki afekte plis pase 30% nan sifas kò a. TEN gen yon pousantaj mòtalite ki depase 20%, souvan akòz enfeksyon ak difikilte pou respire. Sispann medikaman ki lakòz reyaksyon an, bay swen sipò, ak itilize tretman adisyonèl ka amelyore rezilta a. Dènye etid yo te montre ke dwòg tankou cyclosporine, timè necrosis faktè alfa inhibiteurs, ak yon konbinezon de globilin iminitè nan venn ak kortikoterapi yo ka itil, ki baze sou owaza esè kontwole ak analiz de etid miltip.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
 Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review 32520664 
NIH
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.