Urticaria pigmentosa - Urtikè Pigmentosa
Urtikè Pigmentosa (Urticaria pigmentosa) se fòm ki pi komen nan mastositoz kutane. Li se yon maladi ra ki koze pa yon kantite twòp selil mast nan po a ki pwodui itikè oswa blesi sou po a lè irite. Tach wouj oswa mawon souvan parèt sou po a, tipikman alantou pwatrin, fwon, ak do. Selil mast sa yo, lè yo irite (pa egzanp lè w fwote po a oswa ekspoze a chalè), pwodui twòp histamin, sa ki lakòz yon reyaksyon alèjik ki mennen nan itikè ki lokalize nan zòn iritasyon an, pafwa yo rele “siy Darier la”.
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ReferencesMastocytosis se yon kondisyon kote gen yon eksè selil mast, souvan yo jwenn nan divès pati kò a tankou po a, mwèl zo a, ak sistèm dijestif la. Dapre Òganizasyon Mondyal Lasante (OMS), cutaneous mastocytosis ka klase an twa kalite prensipal. Premye kalite a (mastocytomas) konsiste de blesi solitè oswa kèk (≤3). Dezyèm kalite a (urticaria pigmentosa) enplike blesi miltip, tipikman plis pase 10 men mwens pase 100. Dènye kalite a montre patisipasyon toupatou sou po a. Urticaria pigmentosa se fòm ki pi komen nan mastocytosis kutane lakay timoun, men li ka rive tou lakay granmoun. Anjeneral se yon kondisyon ki pa grav e ki souvan amelyore pandan adolesans. Kontrèman ak mastocytosis granmoun, urticaria pigmentosa raman afekte ògàn entèn yo. Youn nan karakteristik ki diferan nan urticaria pigmentosa se tandans li pou lakòz ti tach wouj‑mawon oswa jòn‑mawon ki grate, souvan rele itikè. Tach sa yo anjeneral parèt depi anfans epi yo ka dire tout lavi.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Yon ti fi 6‑zan te vini ak plizyè tach ki gen koulè nwa ki te parèt premye sou po tèt li epi ki te gaye sou figi li ak kò li pandan sis mwa ki sot pase yo. Li mansyone ke tach yo leve, vin wouj, epi yo grate lè yo soufri presyon. Li pa t fè eksperyans bouj, vomisman, dyare, oswa souf anlè, epi istwa medikal pèsonèl li ak fanmi li pa t bay okenn endikasyon ki enpòtan. Apre egzamen an, nou te jwenn plizyè tach nwa sou po tèt li, fwon, figi, ak kou, ansanm ak kèk tach nwa ki te yon ti jan leve sou pwatrin li ak do li. Lè nou fwote tach yo, yo anfle epi demanjezon parèt apre 2 minit, men sentòm yo disparèt apre 15‑20 minit (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
