Keratoacanthoma - Keratoakantoma
☆ Pada hasil Stiftung Warentest tahun 2022 dari Jerman, kepuasan konsumen terhadap ModelDerm hanya sedikit lebih rendah dibandingkan dengan konsultasi telemedis berbayar.
Khas Keratoakantoma (Keratoacanthoma)
relevance score : -100.0%
ReferencesKeratoacanthoma (KA) adalah tumor kulit yang umum, dikenal karena pertumbuhannya yang cepat dan kemampuannya untuk mengalami regresi secara spontan. Biasanya terjadi pada pria lanjut usia dengan kulit putih dan riwayat paparan sinar matahari. Meskipun pengangkatan melalui eksisi atau bedah mikrografik Mohs merupakan terapi utama, terdapat pula berbagai pilihan terapi lain yang tersedia.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) adalah tumor berderajat rendah yang berasal dari kelenjar tertentu pada kulit dan menampakkan kemiripan dengan squamous cell carcinoma (SCC) pada pemeriksaan mikroskopik. Saat ini masih ada perdebatan mengenai apakah KA harus diklasifikasikan sebagai bentuk SCC yang invasif.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Cutaneous squamous cell carcinoma (cSCC) adalah jenis kanker kulit kedua yang paling umum menyerang manusia, terutama pada lansia. Pembedahan biasanya menjadi pilihan utama untuk mengobati cSCC, namun pada beberapa pasien yang tidak dapat atau tidak ingin menjalani operasi, alternatif seperti terapi intralesi dapat dipertimbangkan. Terapi intralesi tradisional (methotrexate atau 5-fluorouracil) telah lama digunakan, namun kini sedang diteliti pendekatan baru seperti imunoterapi intralesi dan viroterapi oncolytic. Berikut ini kami akan membahas berbagai pengobatan intralesi untuk cSCC, mulai dari metode klasik hingga strategi mutakhir.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Di bawah mikroskop, Keratoakantoma (Keratoacanthoma) sangat mirip dengan karsinoma sel skuamosa. Meskipun beberapa ahli patologi mengklasifikasikannya sebagai entitas yang berbeda dan bukan keganasan, sekitar 6 % kasus Keratoakantoma (Keratoacanthoma) dapat berkembang menjadi karsinoma sel skuamosa invasif dan agresif secara klinis dan histologis.
○ Diagnosis dan Pengobatan
#Dermoscopy
#Skin biopsy