Keratoacanthoma - Keratoakantoma
☆ Pada hasil Stiftung Warentest tahun 2022 dari Jerman, kepuasan konsumen terhadap ModelDerm hanya sedikit lebih rendah dibandingkan dengan konsultasi telemedis berbayar.
Khas Keratoakantoma (Keratoacanthoma)
References
Keratoacanthoma (KA) adalah tumor kulit umum yang dikenal karena pertumbuhannya yang cepat dan berpotensi mengalami kemunduran dengan sendirinya. Biasanya terjadi pada pria berusia lanjut dan berkulit putih dengan riwayat kerusakan akibat sinar matahari. Meskipun operasi pengangkatan menggunakan eksisi atau bedah mikrografik Mohs adalah pengobatan yang biasa dilakukan, terdapat berbagai pilihan terapi lain yang tersedia.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) adalah tumor tingkat rendah yang dimulai di kelenjar tertentu di kulit dan terlihat mirip dengan squamous cell carcinoma (SCC) di bawah mikroskop. Ada perdebatan yang sedang berlangsung mengenai apakah KA harus diklasifikasikan sebagai bentuk SCC invasif.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Cutaneous squamous cell carcinoma (cSCC) adalah jenis kanker kedua yang paling umum menyerang manusia, terutama di kalangan lansia. Pembedahan biasanya digunakan untuk mengobati cSCC, namun untuk beberapa pasien yang tidak dapat menjalani operasi atau memilih untuk tidak menjalani operasi, pilihan lain seperti perawatan intralesi dapat dipertimbangkan. Perawatan intralesi tradisional (methotrexate or 5-fluorouracil) telah digunakan, namun terdapat penelitian yang sedang berlangsung mengenai pendekatan baru seperti imunoterapi intralesi dan viroterapi oncolytic. Di sini, kita akan melihat berbagai pengobatan intralesi untuk cSCC, mulai dari metode klasik hingga strategi mutakhir.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Di bawah mikroskop, keratoakantoma (keratoacanthoma) sangat mirip dengan karsinoma sel skuamosa. Meskipun beberapa ahli patologi mengklasifikasikan keratoakantoma (keratoacanthoma) sebagai suatu entitas yang berbeda dan bukan suatu keganasan, sekitar 6% dari keratoakantoma (keratoacanthoma) secara klinis dan histologis berkembang menjadi kanker sel skuamosa yang invasif dan agresif.
○ Diagnosis dan Pengobatan
#Dermoscopy
#Skin biopsy