Acne - Ihe Otutuhttps://en.wikipedia.org/wiki/Acne
Ihe Otutu (Acne) na-esite na mkpụrụ ndụ akpụkpọ ahụ nwụrụ anwụ na mmanụ sitere na akpụkpọ ahụ na-egbochi ntutu isi. Ihe a na-ahụkarị nke ọnọdụ ahụ gụnyere isi ojii ma ọ bụ isi ọcha, pimples, na akpụkpọ mmanu mmanu. Ọ na-emetụta akpụkpọ ahụ nke nwere ọnụ ọgụgụ mmanụ dị elu dị elu, gụnyere ihu, akụkụ elu nke obi, na azụ. Acne na-emekarị n'oge uto ma na-emetụta ihe dị ka 80-90% nke ndị nọ n'afọ iri na ụma na mba ọdịda anyanwụ. Ụfọdụ obodo ime obodo na-akọ na ọnụ ọgụgụ ihe otutu dị ala karịa ndị mepere emepe.

N'ime nwoke na nwanyị abụọ ahụ, homonụ a na-akpọ androgens yiri ka ọ bụ akụkụ nke usoro dị n'okpuru, site n'ịkwalite mmepụta nke sebum. Ihe ọzọ a na-ahụkarị bụ mmụba nke nje bacteria Cutibacterium acnes, nke dị na akpụkpọ ahụ.

A na-ejikarị ọgwụgwọ eme ihe ozugbo na akpụkpọ ahụ emetụtara, dị ka azelaic acid, benzoyl peroxide, na salicylic acid. A na-enweta ọgwụ nje na retinoids n'ụdị a na-etinye na akpụkpọ ahụ ma were ọnụ maka ọgwụgwọ nke otutu. Agbanyeghị, iguzogide ọgwụ nje nwere ike ịmalite n'ihi ọgwụgwọ ọgwụ nje. Ọtụtụ ụdị ọgwụ mgbochi ịmụ nwa nwere ike inye aka gbochie ihe otutu n'ime ụmụ nwanyị. Ngwọta mmalite na ike ike nke ihe otutu site na iji isotretinoin nwere ike inye aka belata mgbagwoju anya na-adịte aka na ndị mmadụ n'otu n'otu.

Ọgwụgwọ
Enwere ike iji gel Adapalene mee ihe n'ọtụtụ ebe n'ihi na ọ na-egbochi ihe nzuzo nke sebum ma nwee mmetụta nke igbochi nlọghachi nke otutu. Adapalene gel nwere ike kpasuo akpụkpọ ahụ iwe ma ọ bụrụ na etinyere ya nke ukwuu na mbụ. Benzoyl peroxide na azelaic acid, n'aka nke ọzọ, nwere ike iji na saịtị ihe otutu na-egbuke egbuke n'ihi na ha na-enyere aka na mbufụt. N'ozuzu, a chọrọ ọgwụgwọ ogologo oge nke ọnwa 1 ma ọ bụ karịa iji hụ mmetụta.

#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream

#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction
☆ Na nsonaazụ Stiftung Warentest nke 2022 sitere na Germany, afọ ojuju ndị ahịa na ModelDerm dị ntakịrị ntakịrị karịa na nyocha telemedicine akwụ ụgwọ.
  • Acne n'akụkụ oke ahụ. Akụkụ elu nke ọkpụkpụ na azụ bụ ebe a na-ahụkarị ihe otutu.
  • Ihe otutu ntì a na-ahụkarị.
  • Acne nwere ike ime n'azụ. Ọ bụrụ na otutu na-apụta na mberede na azụ, drug eruption nwere ike ịtụle.
  • Ihe otutu ọkpọiso a na-ahụkarị. Ihe otutu na oge uto na-amalite n'egedege ihu.
  • N'etiti etiti foto a, a na-ahụ comedone na-acha ọcha na-adịghị emerụ ahụ.
References Diagnosis and treatment of acne 23062156
Ihe otutu, ọnọdụ akpụkpọ anụ kachasị na United States, bụ nsogbu akpụkpọ anụ na-adịgide adịgide. Ọgwụgwọ na-achọ n'ịgbasa isi ihe anọ na-enye aka na ihe otutu: oke mmepụta sebum, mmepụta akpụkpọ anụ, Propionibacterium acnes colonization, na nke na-ebute mbufụt. Topical retinoids na-ejikwa nke ọma ma ọnya ọnya na-adịghị mma site na igbochi na ibelata comedones mgbe ọ na-agwa mbufụt. Benzoyl peroxide, nke dị n'elu-na-counter, bụ ihe na-akpata nje na-enweghị ịkwalite nguzogide nje. Ọ bụ ezie na ọgwụ nje ndị dị n'elu na nke ọnụ na-arụ ọrụ naanị, ijikọta ha na retinoids n'elu na-eme ka ha dị irè. Ịtinye benzoyl peroxide na ọgwụgwọ ọgwụ nje na-ebelata ohere nke iguzogide nje. A na-enye isotretinoin ọnụ, nke akwadoro maka ihe otutu siri ike na nke isi ike, site na mmemme iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
 Guidelines of care for the management of acne vulgaris 26897386
Ọgwụgwọ ndị a na-ahụkarị maka ihe otutu gụnyere benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Ọgwụ nje na-egbu ọnụ abụwo akụkụ bụ isi nke ọgwụgwọ ihe otutu, ọkachasị maka ndị na-agafeghị oke ma ọ bụ nke siri ike. Ha na-arụ ọrụ kacha mma mgbe ejiri ya n'akụkụ retinoid na BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin egosila ihe akaebe nke ịdị irè.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
 Acne Vulgaris: Diagnosis and Treatment 31613567
A na-akwado retinoids dị n'elu mgbe niile maka ịgwọ ihe otutu. Mgbe ị na-eji ọgwụ nje usoro ma ọ bụ n'elu, ọ dị mkpa ijikọta ha na benzoyl peroxide na retinoids, mana naanị ruo izu iri na abụọ. Edebere Isotretinoin maka nnukwu ihe otutu na-azabeghị ọgwụgwọ ndị ọzọ. Ọ bụ ezie na enwere ụfọdụ ihe akaebe maka ọgwụgwọ anụ ahụ dị ka ọgwụgwọ laser na peels kemịkalụ, yana usoro mmekọ ọnụ dị ka venom aṅụ sachara na nri ụfọdụ, arụmọrụ ha ka bụ nke a na-ejighị n'aka.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
 Effects of Diet on Acne and Its Response to Treatment 32748305 
NIH
Ọtụtụ nnyocha elelewo otú nri dị iche iche si emetụta ihe otutu na ndị ọrịa. Ha chọpụtara na ndị nwere ihe otutu na-eri nri ndị nwere obere glycemic dị ala na-enwekarị ntụpọ otutu ma e jiri ya tụnyere ndị na-eri nri nwere nnukwu glycemic dị elu. A mụọkwala mmiri ara ehi gbasara ihe otutu. Ọ dị ka ụfọdụ protein ndị dị na mmiri ara ehi nwere ike inye aka na ọnya karịa abụba ma ọ bụ ọdịnaya mmiri ara ehi zuru oke. Nchọpụta ndị ọzọ lekwasịrị anya na omega-3 fatty acids na γ-linoleic acid. Ọ na-atụ aro na ndị nwere otutu nwere ike irite uru site na iri ọtụtụ azụ na mmanụ dị mma iji mee ka ha na-eri acids fatty. Nnyocha e mere n'oge na-adịbeghị anya banyere probiotics maka ihe otutu na-egosi nsonaazụ na-ekwe nkwa, mana a chọkwuru nyocha iji kwado nchọpụta ndị a mbụ.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.