Ozi ndị ọzọ ― Igbo

Cutaneous angiofibromas nwere ike ịpụta n'akụkụ dị iche iche nke ahụ. Na ihu, a na-akpọkarị ha dị ka papules fibrous ma ọ bụ adenoma sebaceum; na amụ, a na-akpọ ha pearly penile papules ; n'okpuru ntu, a na-akpọ ha periungual angiofibromas ma ọ bụ etuto Koenen; na n'ọnụ, a na-akpọ ha fibromas. Angiofibromas ihu bụ ihe ama ama nke tuberous sclerosis (TS) , ọrịa ketara eketa na-emetụta akpụkpọ ahụ, akụrụ, obi, ụbụrụ, na ngụgụ. Ha na-etolite na ihu n'oge nwata ma ọ bụ n'oge ha toro na ndị nwere TS. A na-ewere angiofibromas ihu atọ ma ọ bụ karịa ma ọ bụ abụọ ma ọ bụ karịa periungual angiofibromas dị mkpa n'ịchọpụta TS. Na mgbakwunye, otutu angiofibromas ihu nwere ike ịdị na ọnọdụ (multiple endocrine neoplasia type 1 (MEN-1) na Birt-Hogg-Dubé syndrome) . A na-ahụ Pearly penile papules n'akụkụ akụkụ coronal na sulcus nke amụ. Ha bụ ọnyà na-adịgide adịgide, nke na-enweghị mgbu na-ahụkarị na ụmụ nwoke a na-ebighị úgwù.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.