Drug eruption
https://en.wikipedia.org/wiki/Drug_eruption
☆ Na nsonaazụ Stiftung Warentest nke 2022 sitere na Germany, afọ ojuju ndị ahịa na ModelDerm dị ntakịrị ntakịrị karịa na nyocha telemedicine akwụ ụgwọ. 

A na-eji Drug eruption na-emetụta ahụ dum.

N'ebe ọ na-emetụta ahụ nke ukwuu, a ga-atụle nyocha nke Drug eruption kama ịkpọtụrụ dermatitis.


AGEP (Acute generalized exanthematous pustulosis) bụ ụdị ọkụ ọkụ ọgwụ.
relevance score : -100.0%
References
Current Perspectives on Severe Drug Eruption 34273058 NIH
Mmeghachi omume akpụkpọ ahụ nke ọgwụ, nke a maara dị ka mgbawa ọgwụ, nwere ike ịdị njọ mgbe ụfọdụ. A na-ewere mmeghachi omume ndị a siri ike, nke a na-akpọ severe cutaneous adverse drug reactions (SCARs) , dị ka ihe egwu ndụ. Ha gụnyere ọnọdụ dịka Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Ọ bụ ezie na SCARs dị ụkọ, ihe dị ka 2% nke ndị ọrịa nọ n'ụlọ ọgwụ na-enweta ha.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Fixed drug eruption - Case reports 35918090 NIH
Otu nwanyị dị afọ 31 gara ngalaba na-ahụ maka akpụkpọ ahụ nke nwere ihe mgbochi uhie na-enweghị mgbu n'elu ụkwụ aka nri ya. O were otu dose nke doxycycline (100 mg) ụbọchị gara aga, na-eso ọgwụgwọ laser picosecond maka ọnya otutu. N'afọ gara aga, ọ nwetara ụdị okwu ahụ n'otu ebe ahụ mgbe ọ nwụsịrị otu dose nke doxycycline ọgwụgwọ laser post-laser. Ọ nweghị nnukwu akụkọ gbasara ahụike yana enweghị akara ngosi ndị ọzọ, dị ka ahụ ọkụ, mpaghara ma ọ bụ ahụ ya niile.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson Syndrome 29083827 NIH
Stevens-Johnson syndrome (SJS) na toxic epidermal necrolysis (TEN) bụ ụdị abụọ nke mmeghachi omume akpụkpọ ahụ siri ike, dị iche na ọnọdụ akpụkpọ ahụ ndị ọzọ dị ka erythema multiforme major na ọrịa akpụkpọ anụ staphylococcal scalded, yana mmeghachi omume ọgwụ. SJS/TEN bụ mmeghachi omume na-adịghị ahụkebe na nke siri ike na-akpata mmebi akpụkpọ anụ na akpụkpọ anụ mucous, na-enwekarị mgbaàmà usoro. N'ihe karịrị 80% nke ikpe, ọgwụ bụ ihe kpatara ya.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
A na-achọpụta mgbawa ọgwụ na-abụkarị site na akụkọ ahụike na nyocha ụlọ ọgwụ. Biopsy akpụkpọ ahụ, nyocha ọbara ma ọ bụ nyocha mgbochi ọrịa nwekwara ike ịba uru.
Ihe atụ nke ọgwụ ndị a na-ahụkarị na-akpata mgbawa bụ ọgwụ nje na ọgwụ nje ndị ọzọ, ọgwụ sulfa, ọgwụ ndị na-abụghị steroidal anti-inflammatory drugs (NSAIDs), ọgwụ chemotherapy maka ọrịa ọjọọ, anticonvulsants na psychotropic ọgwụ.
○ Diagnosis na ọgwụgwọ
Ọ bụrụ na ị nwere ahụ ọkụ (mmụba okpomọkụ nke ahụ), ị kwesịrị ịchọ nlekọta ahụike ozugbo enwere ike. Ekwesịrị ịkwụsị ọgwụ a na-enyo enyo (dịka ọgwụ nje, ọgwụ ndị na-abụghị steroidal anti-inflammatory). Tupu ị gaa ụlọ ọgwụ, ọgwụ antihistamines dị ka cetirizine ma ọ bụ loratadine nwere ike inye aka maka itching na ọkụ ọkụ.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Nnwale ọbara (CBC, LFT, ọnụ ọgụgụ eosinophil)
Steroid nke ọnụ na antihistamines nwere ndenye ọgwụ