Intraepithelial carcinoma (Bowen disease)https://en.wikipedia.org/wiki/Squamous_cell_skin_cancer
Intraepithelial carcinoma (Bowen disease) na-egosi mkpụrụ ndụ squamous nke na-amụba n'ókè epidermis dum. Akpụkpọ ahụ a dị naanị n'epidermis, ọ naghị agafe n'ime dermis. A na-ekewa ọrịa a n'ụzọ nkà na ụzụ dị ka ọrịa kansa, mana ọ naghị emerụ ahụ dịka cancer nkịtị (ya bụ, ọ bụ ọrịa kansa nwere ezigbo prognosis).

Ọ na-apụta dịka mpaghara nwere agba uhie (erythematous), akpịrịkpa ma ọ bụ ahịhịa juru n'ahụ. Ebe a na-ahụkarị bụ ụkwụ.

A na-agwọ ya site n'ịhọrọ n'etiti ọgwụgwọ dị iche iche dịka cryotherapy, curettage, cautery, photodynamic therapy, ma ọ bụ excision.

Diagnosis na ọgwụgwọ
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy
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  • Enwere ike ịchọpụta ikpe Intraepithelial carcinoma (Bowen disease) dị ka ihe nfụkasị ahụ na-adịte aka.
  • Cutaneous horn ― N'adịghị ka warts, ọ na-apụta dị ka nodule siri ike, ma biopsy dị mkpa iji wepụ ihe ọjọọ.
  • Ọ bụrụ na ọnya na-adịgide ogologo oge, a ga-atụle kansa anụ ahụ.
  • Intraepithelial carcinoma (Bowen disease) ― Ọrịa a na-ahụkarị
  • N'okwu a, Irritated seborrheic keratosis nwekwara ike ịtụle dị ka ihe nwere ike ibute nchọpụta dị iche.
  • A na-ehiekarị ụzọ maka nsogbu nrịanrịa, dịka ọmụmaatụ, nummular eczema.
  • Intraepithelial carcinoma (Bowen disease) ― Ọrịa a na-ahụkarị
  • Ihe ọzọ na-ahụkarị na-egosi ụdị odịdị ahụ na ọnọdụ nfụkasị ahụ.
References Bowen's Disease 35287414 
NIH
Bowen's disease (BD) bụ ụdị ọrịa kansa anụ ahụ nke na-amalite na oyi akwa akpụkpọ ahụ (epidermis). Ọ na-adịkarị n’ụlọ ndị Caucasians ma na-emekarị n’akụkụ ebe a na-ekpughe ìhè anyanwụ, mana ọ nwere ike ịpụta n’ebe ọzọ. BD na-apụta dịka otu ọnya. A na-ahụkarị BD dị ka akara ịdọ aka ná ntị tupu ụdị ọrịa cancer anụ ahụ dị njọ karị amalite. Iji chọpụta BD, ndị dọkịta na-adaberekarị na nyocha anụ ahụ n’ime microscope (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
 Bowen disease - Case reports 17001052 
NIH
Bowen's disease na-emetụkarị ndị mmadụ ruru afọ 60. Ihe ndị bụ isi na-eme ka ize ndụ gụnyere ikpughe ogologo oge n’anwụ, usoro ahụ ji alụso ọrịa ọgụ adịghị ike, ikpughe arsenic, na ọrịa HPV n’akpụkpọ. A na-ejikọta ụdị HPV 16, 18, 34, na 48 na Bowen's disease n’ime mpaghara genital. Ntinye aka HPV n'okwu ndị na-abụghị genital adịchaghị nke ọma.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.