Intraepithelial carcinoma (Bowen disease)
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Enwere ike ịchọpụtakarị ikpe Intraepithelial carcinoma (Bowen disease) dị ka ihe nfụkasị ahụ na-adịte aka.
References
Bowen's disease (BD) bụ ụdị ọrịa kansa anụ ahụ nke na-amalite na oyi akwa akpụkpọ ahụ (epidermis) . Ọ na-adịkarị na ndị Caucasians ma na-emekarị na mpaghara ndị ekpughere ìhè anyanwụ, mana ọ nwere ike ịpụta n'ebe ọzọ. BD na-apụtakarị dị ka otu ọnya. A na-ahụkarị BD dị ka akara ịdọ aka ná ntị tupu ụdị ọrịa cancer anụ ahụ dị njọ karị amalite. Iji chọpụta BD, ndị dọkịta na-adaberekarị na nyocha anụ ahụ n'okpuru microscope (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease na-emetụtakarị ndị ọcha gbara afọ 60. Ihe ndị bụ isi dị ize ndụ gụnyere ikpughe ogologo oge anwụ, usoro ahụ ji alụso ọrịa ọgụ adịghị ike, ikpughe arsenic, na ọrịa HPV akpụkpọ. A na-ejikọta ụdị HPV 16, 18, 34, na 48 na ọrịa Bowen na mpaghara genital. Ntinye aka nke HPV n'okwu ndị na-abụghị nke genital adịchaghị nke ọma.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Ọ na-apụtakarị dị ka ebe erythematous, akpịrịkpa ma ọ bụ ahịhịa juru ebe ọ bụla na ahụ. Ebe a na-ahụkarị bụ ụkwụ ala.
A na-agwọ ya site na nhọrọ ọgwụgwọ dị iche iche dị ka cryotherapy, curettage, cautery, photodynamic therapy, ma ọ bụ mpụ nke ọnya.
○ Diagnosis na ọgwụgwọ
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy