Juvenile xanthogranuloma
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References
Juvenile xanthogranuloma (JXG) bụ ọnọdụ a na-ahụkarị yana ụdị non-Langerhans cell histiocytic disorder kachasị na ụmụaka. N'ihe dị ka 75% nke ikpe, ọnya ndị a na-apụta n'ime afọ mbụ nke ndụ, na ihe karịrị 15-20% nke ndị ọrịa nwere ha site na ọmụmụ. Ọ bụ ezie na ndị okenye na-adịghị ahụkebe, JXG na-emekarị na ndị mmadụ n'afọ iri abụọ ruo iri atọ, na ọtụtụ ndị ọrịa toro eto nwere naanị otu ọnya. N'ụlọ ọgwụ, ọ na-egosi dị ka otu ma ọ bụ ọtụtụ odo-oroma-aja aja siri ike gbambọm ma ọ bụ akpụ, tumadi na ihu, olu, na elu ahụ. Ọnya ọnụ bụ ihe a na-adịghị ahụkebe mana ọ nwere ike ịpụta dị ka mkpọ odo n'akụkụ ire ma ọ bụ n'ebe ọzọ n'ọnụ, ikekwe na-ebute ọnya na ọbara ọgbụgba. Ahụhụ akpụkpọ ahụ anaghị ebutekarị mgbaàmà ma na-apụ n'onwe ha n'ime ọtụtụ afọ. Ọ bụ ezie na ọ dị ụkọ, itinye aka na anya bụ ihe a na-ahụkarị karịa akpụkpọ ahụ, na-esote ntinye aka ngụgụ. Ocular JXG na-emetụtakarị naanị otu anya ma na-apụta n'ihe na-erughị 0. 5 % nke ndị ọrịa, n'agbanyeghị na ihe dị ka 40% nke ndị na-etinye aka na anya nwekwara ọtụtụ ọnya anụ ahụ mgbe a chọpụtara ya.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) bụ ọrịa a na-adịghị ahụkebe, nke na-adịghị mma bụ akụkụ nke nnukwu ụdị non-Langerhans cell histiocytoses. Ha na-egosipụtakarị dị ka otu ma ọ bụ karịa na-acha uhie uhie ma ọ bụ odo odo, na-ahụkarị n'isi ma ọ bụ n'olu. Ọtụtụ JXG na-etolite ma mgbe a mụrụ ya ma ọ bụ n'ime afọ mbụ nke ndụ. Ọ bụ ezie na ọ bụ ihe a na-adịghị ahụkebe, mgbe ụfọdụ, ha nwere ike imetụta ebe karịrị akpụkpọ ahụ, na itinye aka na anya bụ ihe a ga-ekiri dịka akwụkwọ ndị dị adị. N'ozuzu, JXGs na akpụkpọ ahụ na-apụ n'onwe ha ma ọ dịghị mkpa ọgwụgwọ.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Ọnya anya na-egosipụta ihe ruru 10% nke ndị nwere JXG ma nwee ike imetụta ọhụụ ha. Ọ bụ ezie na ọnya akpụkpọ ahụ na-apụkarị n'onwe ya, ọnya anya adịghị adịkarị mma ma chọọ ọgwụgwọ.