Syphilis
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Chancres – ọrịa mbụ nke syphilis sitere na Treponema pallidum
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ReferencesSyphilis bụ ọrịa a na-ebute site n'ịkpa mmekọahụ site na nje bacteria Treponema pallidum. N'ime ọmụmụ ihe a, anyị lekwasịrị anya na ndị ọrịa 57, dị afọ 18 ruo 68, nwere syphilis nke abụọ.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis bụ ọrịa nje nke Treponema pallidum kpatara. Ọ nwere ike iṅomi ọrịa dị iche iche, na-enweta aha ‘great imitator’. Syphilis ka na-emetụta nde mmadụ n'ụwa niile, mana enwere ike iji penicillin gwọọ ya nke ọma.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum na-ebute ọrịa syphilis site n'ịkpa mmekọ nwoke na nwanyị ma ọ bụ site n'ịnyefe site n'aka nne n'oge ime. N'agbanyeghị na e nwere ule dị mfe iji chọpụta ya, yana ọgwụgwọ penicillin n'otu ogbugba nke na-arụ ọrụ nke ọma, syphilis ka na-aghọ nnukwu nsogbu n'ụwa niile. Nke a bụ eziokwu karịsịa n'etiti ndị ikom na-eme mmekọahụ na ndị ikom (MSM) na mba ndị nwere akụ na ụba dị elu. Ọ bụ ezie na ụfọdụ mba nwere ego pere mpe enwetala ebumnuche WHO iji kwụsị nnyefe syphilis site n'aka nne, enwere mụbaa nchegbu banyere mmụba syphilis n'etiti MSM, nke na-emekarị ka ọ bụrụ ihe ize ndụ maka HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Imeju na‑ebuwanye ibu: A na‑ahụkarị ya ma nwee ike ime n’akụkụ splin gbasaara. Inyocha biopsy imeju n’okpuru microscopy gbara ọchịchịrị nwere ike ikpughe ọnụnọ spirochete. Nnwale ọrụ imeju nwere ike igosi ihe adịghị mma. (2) Akpụkpọ ahụ na‑acha odo odo (Jaundice): Ma mmadụ na‑egosi jaundice, ọ dabere n’otú imeju si emetụta ya. (3) Imi na‑agba ọsọ: Ọtụtụ mgbe, ọ bụ otu n’ime ihe ịrịba ama mbụ, na‑abụkarị n’ime izu mbụ mgbe amụrụ nwa. (4) Ọkpụkpụ Lymph Swollen: Ọzịza nke lymph nodes, na‑enwekarị mgbu, na‑adịkarịkwa. (5) Ihe nfụkasị akpụkpọ ahụ: ọkụ ọkụ na‑apụta otu izu ma ọ bụ abụọ ka imi gbachara. Ị nwere ike ịhụ obere ntụpọ uhie ma ọ bụ pink n’azụ, n’ukwu, n’akụkụ ụkwụ, na ọbụ n’ala ụkwụ. Ihe ọkụ a nwere ike ịga n’ihu, na‑akpụ akpụ, na nchikota.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Nchọpụta na Ọgwụgwọ
Enwere ike iji VDRL na RPR chọpụta ọrịa syphilis n'oge mbụ. Nnwale FTA-ABS bụ ule pụrụ iche a na-eji lelee akụkọ ihe mere eme ọrịa gara aga. A na-eji penicillin agwọ ọrịa syphilis.