Syphilis
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Chancres - ọrịa mbụ syphilitic sitere na Treponema pallidum
References
Syphilis bụ ọrịa a na-ebute site ná mmekọahụ nke nje bacteria Treponema pallidum kpatara. N'ime ọmụmụ ihe a, anyị na-elekwasị anya na ndị ọrịa 57 dị afọ 18-68 nwere syphilis nke abụọ.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis bụ ọrịa nje nke Treponema pallidum kpatara. Ọ nwere ike iṅomi ọrịa dị iche iche, na-enweta ya aha otutu great imitator. Sịphilis ka na-emetụta nde mmadụ n'ụwa niile mana enwere ike iji penicillin gwọọ ya nke ọma.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum na-ebute ọrịa syphilis site na mmekọ nwoke na nwanyị ma ọ bụ site na nne na nwa ọhụrụ n'oge ime. N'agbanyeghị na enwere ule dị mfe iji chọpụta ya na ọgwụgwọ otu ogbugba penicillin na-eme ogologo oge na-arụ ọrụ nke ọma, syphilis na-aghọkwa nnukwu nsogbu ọzọ n'ụwa niile. Nke a bụ eziokwu karịsịa n'etiti ndị ikom na-enwe mmekọahụ na ndị ikom (MSM) na mba ndị nwere nnukwu ego na nke etiti. Ọ bụ ezie na ụfọdụ mba ndị na-akpata obere ego ezutewo ebumnuche WHO iji kwụsị syphilis na-esi na nne na-ebufe nwa ọhụrụ, enwere ịrị elu na-echegbu onwe ya na syphilis n'etiti MSM bu nje HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Imeju Na-ebuwanye ibu: A na-ahụkarị nke a ma nwee ike ime n'akụkụ splin gbasaara. Inyocha biopsy imeju n'okpuru microscopy gbara ọchịchịrị nwere ike ikpughe ọnụnọ nke spirochete. Nnwale ọrụ imeju nwere ike igosi ihe adịghị mma. (2) Akpụkpọ ahụ na-acha odo odo (Jaundice) : Ma mmadụ ọ̀ na-egosi jaundice na-adabere n’otú imeju na-emetụta ya. (3) Imi na-agba ọsọ: Ọtụtụ mgbe, otu n'ime ihe ịrịba ama mbụ, na-abụkarị n'ime izu mbụ mgbe amuchara nwa. (4) Ọkpụkpụ Lymph Swollen: Ọzịza nke ọnụ ọnụ lymph, na-enwekarị mgbu, na-adịkarịkwa. (5) Ihe nfụkasị akpụkpọ ahụ: ọkụ ọkụ na-apụtakarị otu izu ma ọ bụ abụọ ka imi imi gbachara. Ị nwere ike ịhụ obere ntụpọ uhie ma ọ bụ pink n'azụ, ukwu, apata ụkwụ, na ọbụ ụkwụ. Ihe ọkụ ọkụ a nwere ike ịga n'ihu na-akpụ akpụ na nchikota.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Nchọpụta na Ọgwụgwọ
Enwere ike iji VDRL na RPR gosipụta ọrịa na nso nso a maka syphilis. Nnwale FTA-ABS bụ ule a kapịrị ọnụ ma enwere ike iji ya lelee akụkọ ihe mere eme ọrịa gara aga. A na-eji penicillin agwọ ọrịa syphilis.