Urticarial vasculitis
https://en.wikipedia.org/wiki/Urticarial_vasculitis
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References
Urticarial vasculitis 34222586 NIH
Urticarial vasculitis bụ ọnọdụ a na-adịghị ahụkebe nke urticarial lesions na-adịte aka ma ọ bụ ugboro ugboro. Ọ bụ ezie na mgbaàmà akpụkpọ ahụ ya nwere ike ịdị ka urticaria, ha pụrụ iche n'ihi na urticaria na-arapara n'ahụ maka opekempe awa 24 ma nwee ike ịkpata ntụpọ ojii mgbe ọ dachara. Ọ bụ ezie na a na-amabeghị ihe kpatara ya, mgbe ụfọdụ ọgwụ ụfọdụ, ọrịa na-efe efe, ọrịa autoimmune, ọrịa ọbara, ma ọ bụ ọrịa cancer nwere ike ịkpalite ya. Ụfọdụ ọmụmụ ejikọtala ya na ọrịa COVID-19 na H1N1. Ọ nwekwara ike imetụta akụkụ ahụ ndị ọzọ dị ka musculoskeletal, renal, pulmonary, gastrointestinal, ocular. Ọ bụ ezie na ụfọdụ ụdị nyocha anụ ahụ nwere ike ịkwado nchoputa ahụ, ọ bụghị mgbe niile ka ọ dị mkpa. Antibiotics, dapsone, colchicine, ma ọ bụ hydroxychloroquine maka ndị dị nro. Maka ikpe ndị ka njọ, methotrexate ma ọ bụ corticosteroids nwere ike ịdị mkpa. Na nso nso a, rituximab, omalizumab, interleukin-1 inhibitors egosila nkwa maka ikpe siri ike.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Faropenem-induced urticarial vasculitis - Case reports 33580928Otu nwoke dị afọ 35 batara na akụkọ ihe mere eme nke ụbọchị iri na ise nke na-acha uhie uhie na-egbuke egbuke, na-egbu mgbu na akpụkpọ ụkwụ (thighs) na ụkwụ (legs), yana mgbu nkwonkwo. O nwere urinary tract infection (UTI) otu izu tupu ọkụ ọkụ apụta. Akpụkpọ ahụ ya gosiri ọtụtụ ihe dị nro, yiri mgbanaka, nke na-acha uhie uhie, n'akụkụ abụọ nke akpụkpọ ụkwụ (thighs) ya na ụkwụ (legs) ya. E nyere ya prednisolone (40mg / ụbọchị) maka otu izu yana ọgwụ antihistamine na-adịghị ehi ụra (fexofenadine). N'ime otu izu, ụjọ (rashes) niile kwụsịrị kpamkpam. Enwekwaghị ụjọ (rashes) ọzọ n'ime ọnwa 6 na-esote nke nyocha oge niile.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Ọgwụgwọ ― OTC Ọgwụ
Ọ bụrụ na ị nwere ahụ ọkụ (fever), anyị na-akwado ka ị chọọ nlekọta ahụike ozugbo.
Ekwesịrị ịkwụsị ọgwụ a na-enyo enyo. (dịka ọmụmaatụ, antibiotics (ogwu nje), non‑steroidal anti‑inflammatory drugs (ogwu mgbochi mkpali na-abụghị steroidal))
Ọgwụ antihistamines dị ka cetirizine ma ọ bụ loratadine maka itching.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
OTC steroid ointments nwere ike ghara ịdị irè maka ike dị ala. Ekwesịrị itinye akwụkwọ maka ihe karịrị otu izu iji hụ mmelite.
#Hydrocortisone ointment