Drug eruption
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Drug eruption einkennist af því að hafa áhrif á allan líkamann.
References
Húðviðbrögð af völdum lyfja, þekkt sem lyfjagos, geta stundum verið alvarleg. Þessi alvarlegu viðbrögð, sem kallast severe cutaneous adverse drug reactions (SCARs) , eru talin lífshættuleg. Þau innihalda skilyrði eins og Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Þó að SCARs sé sjaldgæft, upplifa um 2% sjúklinga á sjúkrahúsi þær.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
31 árs kona kom á húðdeildina með sársaukalausan rauðan blett efst á hægri fæti. Hún tók einn skammt af doxýcýklíni (100 mg) daginn áður, eftir píkósekúndu lasermeðferð við unglingabólum. Á síðasta ári upplifði hún svipað vandamál á sama stað eftir að hafa tekið sama skammt af doxýcýklíni eftir leysigeislun. Hún hefur enga marktæka sjúkrasögu og engin önnur einkenni, eins og hiti, staðbundið eða um allan líkamann.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) og toxic epidermal necrolysis (TEN) eru tvenns konar alvarleg húðviðbrögð, ólík öðrum húðsjúkdómum eins og erythema multiforme major og staphylococcal scalded skin heilkenni, auk lyfjaviðbragða. SJS/TEN er sjaldgæf og alvarleg viðbrögð sem valda víðtækum húð- og slímhúðskemmdum, oft með almennum einkennum. Í yfir 80% tilvika eru lyf orsökin.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Lyfjagos greinast aðallega út frá sjúkrasögu og klínískri skoðun. Húðvefjasýni, blóðprufur eða ónæmispróf geta einnig verið gagnleg.
Dæmi um algeng lyf sem valda gosinu eru sýklalyf og önnur örverueyðandi lyf, súlfalyf, bólgueyðandi gigtarlyf (NSAID), krabbameinslyf við illkynja sjúkdóma, krampalyf og geðlyf.
○ Greining og meðferð
Ef þú ert með hita (hækkan líkamshita) ættir þú að leita læknis eins fljótt og auðið er. Hætta skal lyfinu sem grunur leikur á (t.d. sýklalyfjum, bólgueyðandi lyfjum sem ekki eru sterar). Áður en þú heimsækir sjúkrahús geta andhistamín til inntöku eins og cetirizin eða loratadin hjálpað til við kláða og útbrot.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Blóðpróf (CBC, LFT, eósínófílafjöldi)
Sterar til inntöku og andhistamín með lyfseðli læknis