Dermatofibroma
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Caso tipico di Dermatofibroma ― Un nodulo duro sull'arto. Dermatofibroma è un tumore benigno relativamente comune.
References
Dermatofibroma è una condizione comune della pelle che si riscontra soprattutto sulle braccia o sulle gambe. Appare come grumi sodi sotto la pelle, spesso di dimensioni inferiori a 1 centimetro. Sebbene di solito sia indolore, può essere collegato a ferite minori del passato, come punture di insetti o punture di spine. I dermatofibromi possono colpire chiunque, ma sono più comuni nelle donne di età compresa tra 20 e 40 anni. Sono generalmente benigni, ma a volte possono ripresentarsi dopo la rimozione. È importante differenziare i dermatofibromi da un tumore cutaneo più aggressivo chiamato dermatofibrosarcoma protuberans.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Il trattamento preferito per lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts è la rimozione chirurgica. Cherry angiomas and sebaceous hyperplasia sono comunemente trattati con terapia laser o elettroessiccazione. La crioterapia e l'escissione con rasatura sono scelte popolari per acrochordons and seborrheic keratoses. Se un medico di famiglia si sente incerto sulla diagnosi o sul trattamento di una lesione, o se una biopsia conferma il melanoma, si raccomanda di rivolgersi a uno specialista.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
I dermatofibromi possono formarsi come reazione a lesioni precedenti come punture di insetti o punture di spine. I dermatofibromi sono classificati come lesioni cutanee benigne, il che significa che sono completamente innocui, sebbene i dermatofibromi possano essere confusi con una varietà di tumori sottocutanei. I dermatofibromi penetranti in profondità possono essere difficili da distinguere, anche istologicamente, dai rari tumori fibroistocitici maligni come il "dermatofibrosarcoma protuberans".
○ Diagnosi e trattamento
La maggior parte è benigna, ma lesioni di grandi dimensioni (> 5 mm) possono richiedere una biopsia.
#Dermoscopy
#Skin biopsy